Thiophen-3-amine hydrochloride CAS 25475-76-7
| CAS No. | 25475-76-7 |
| Molecular Formula | C4H5NS |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Thiophen-3-amine hydrochloride.
Thiophen-3-amine hydrochloride (CAS 25475-76-7), molecular formula C4H5NSHCl and molecular weight 135.61 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Thiophen-3-amine hydrochloride (C4H5NSHCl) contains a nitrile group, sulfur-containing functionality, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 2.0, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 135.61 g/mol, it falls into the low-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Thiophen-3-amine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H5NS HCl |
| Molecular Weight | 135.61 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Thiophen Standards
- 4-(Thiophen-2-ylmethyl)benzonitrile (CAS 100005-79-6)
- 1-(Thiophen-2-yl)cyclohexane-1-carboxylic acid (CAS 100058-72-8)
- 1-Methyl-4-(thiophen-2-yl)piperidin-4-ol (CAS 100131-91-7)
- 1-(Thiophen-2-yl)cyclohexan-1-amine (CAS 100133-00-4)
- Ethyl 2-((5-(3-(thiophen-2-yl)ureido)-1,3,4-thiadiazol-2-yl)thio)acetate (CAS 1001830-00-7)
- 2-((5-(3-(Thiophen-2-yl)ureido)-1,3,4-thiadiazol-2-yl)thio)acetamide (CAS 1002043-11-9)
- 4-(Thiophen-2-ylmethyl)benzoic acid (CAS 1002727-90-3)
- Methyl(thiophen-2-yl)cyanocarbonimidodithioate (CAS 100477-76-7)
Recommended Standards
- 4-methyl-3-(pyridin-2-ylsulfonyl)thiophene-2-carbaldehyde (CAS 1258283-07-6)
- 7-(2-Aminoethyl)pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidin-6(7H)-one (CAS 1374509-70-2)
- Lanthanum Nickel Cobalt Alloy (CAS 130469-99-7)
- Galantamine EP Impurity C (CAS 21133-52-8)
- (2S,3S)-2-(4-Ethoxyphenyl)-1-ethyl-6-oxopiperidine-3-carboxylic Acid (CAS 1391392-70-3)
- 4-Amino-5-chloro-6-(difluoromethyl)pyridine-3-sulfonyl chloride (CAS 1805101-69-2)
- 6-Amino-4-[[3-chloro-4-(2-pyridyloxy)phenyl]amino]-7-ethoxyquinoline-3-carbonitrile (CAS 1956340-48-9)
- methyl 2-(3-oxo-2-pentylcyclopentyl)acetate (CAS 2630-39-9)
- (3-Fluoro-4-methoxyphenyl)(methyl)sulfane (CAS 66624-36-0)
- Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 75976-10-2)
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