Vericiguat Impurity 67 CAS 2755814-39-0
| CAS No. | 2755814-39-0 |
| Molecular Formula | C18H14F2N8O |
| Molecular Weight | 396.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Vericiguat Impurity 67 (CAS 2755814-39-0, C18H14F2N8O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Vericiguat Impurity 67 (C18H14F2N8O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Vericiguat Impurity 67 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H14F2N8O |
| Molecular Weight | 396.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 8 |
Related Vericiguat Standards
- Vericiguat Impurity 4 (CAS CATO-C4X-28964)
- Vericiguat Impurity 25 (CAS CATO-C4X-289625)
- Vericiguat Impurity 100 (CAS 1011527-86-8)
- Vericiguat Impurity 3 (CAS 3052969-91-9)
- Vericiguat impurity 47 (CAS CATO-C4X-289647)
- Vericiguat Impurity 69 (CAS CATO-C4X-289669)
- Vericiguat impurity 56 (CAS CATO-C4X-289656)
- Vericiguat impurity 53 (CAS CATO-C4X-289653)
Recommended Standards
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- Metoclopramide EP Impurity A (CAS 5608-13-9)
- Glipizide EP Impurity G (CAS 33288-74-3)
- Ticagrelor Impurity 150 (CAS 220349-80-4)
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- Prilocaine Impurity 10 (CAS CATO-C4X-193410)
- 5,5,5-Trifluoro-3-iodopentan-1-ol (CAS 1379365-21-5)
- 2-((4-Ethylphenyl)amino)-2-(1-methyl-1H-pyrazol-4-yl)acetonitrile (CAS 1170500-39-6)
- Des-Ser39-Tirzepatide (CAS CATO-CPTD788936)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com