Ibrutinib Impurity 74 CAS 2554619-82-6

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.2554619-82-6
Molecular FormulaC25H26N6O3
Molecular Weight458.51 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Ibrutinib Impurity 74 CAS 2554619-82-6 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 458.51 g/mol gives Ibrutinib Impurity 74 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Ibrutinib Impurity 74 (CAS 2554619-82-6) is a certified pharmaceutical impurity reference standard with the molecular formula C25H26N6O3 and a molecular weight of 458.51 g/mol.

Based on its molecular formula C25H26N6O3, Ibrutinib Impurity 74 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 458.51 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Ibrutinib Impurity 74 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC25H26N6O3
Molecular Weight458.51 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)16.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2001
Nitrogen Atoms6

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