Ibrutinib Impurity 42 CAS 2052279-49-7
| CAS No. | 2052279-49-7 |
| Molecular Formula | C25H24N6O3 |
| Molecular Weight | 456.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Ibrutinib Impurity 42 (CAS 2052279-49-7), a pharmacopoeial impurity reference standard (molecular formula C25H24N6O3, MW 456.50 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Ibrutinib Impurity 42 (C25H24N6O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 17.0, corresponding to approximately 17 ring(s) or double-bond equivalent(s). With a molecular weight of 456.50 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Ibrutinib Impurity 42 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H24N6O3 |
| Molecular Weight | 456.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 6 |
Related Ibrutinib Standards
- Ibrutinib Impurity 105 (CAS 2988167-31-1)
- Ibrutinib Impurity 12 (CAS 2417548-74-2)
- Ibrutinib Impurity 72 (CAS CATO-C4X-106472)
- Ibrutinib Impurity 75 (CAS 2437254-47-0)
- Ibrutinib Impurity 150 (CAS 1839099-23-8)
- Ibrutinib Impurity 113 (CAS CATO-C4X-1064113)
- Ibrutinib Impurity N1 (CAS 1838132-94-7)
- Ibrutinib Impurity 171 (CAS CATO-C4X-1064171)
Recommended Standards
- N,N-Diethyl-3-[5-mercapto-4-(3-trifluoromethyl-phenyl)-4H-[1,2,4]triazol-3-yl]-benzenesulfonamide (CAS 721415-63-0)
- Imatinib Impurity 67 (CAS 2031255-25-9)
- 4-Methyl-N-{[4-methyl-5-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)-4H-1,2,4-triazol-3-yl]methyl}benzene-1-sulfonamide (CAS 338953-95-0)
- Ademetionine Impurity 2 (CAS CATO-C4X-21522)
- Ceritinib Impurity 61 (CAS CATO-C4X-104861)
- Delafloxacin impurity 38 (CAS 906088-99-1)
- Daptomycin Impurity 40 (CAS CATO-C4X-137840)
- N-[(3-fluorophenyl)methyl]cyclobutanamine (CAS 1250108-36-1)
- 2-Oxo-1-phenyl-1,2-dihydro-1,8-naphthyridine-3-carboxylic acid (CAS 1239164-92-1)
- Methyl 2-hydroxy-3,5-diiodobenzoate (CAS 18071-50-6)
- Atorvastatin lactam methyl ester (CAS 1795790-02-1)
- (2-Methoxy-5-methylpyridin-3-yl)methanol (CAS 351410-48-5)
- 4-Chloro-3-[(dimethylamino)methyl]aniline (CAS 697305-72-9)
- A-18-F-NH2; Morphine Modulating Neuropeptide (CAS 99588-52-0)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com