Cefuroxime Impurity 89 CAS CATO-C4X-124589
| CAS No. | CATO-C4X-124589 |
| Molecular Formula | C17H22N4O7S2 |
| Molecular Weight | 458.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Cefuroxime Impurity 89 (CAS CATO-C4X-124589, C17H22N4O7S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Cefuroxime Impurity 89 (C17H22N4O7S2) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H22N4O7S2 |
| Molecular Weight | 458.51 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Cefuroxime Standards
- Cefuroxime Impurity 88 (CAS CATO-C4X-124588)
- Cefuroxime Impurity 24 (CAS 929531-97-5)
- Cefuroxime Impurity 58 (CAS CATO-C4X-124558)
- Cefuroxime Impurity 85 (CAS CATO-C4X-124585)
- Cefuroxime Axetil Impurity 16 (CAS CATO-C4X-143616)
- Cefuroxime Impurity 91 (CAS CATO-C4X-124591)
- Cefuroxime Impurity 96 (CAS CATO-C4X-124596)
- Cefuroxime Impurity 11 (CAS CATO-C4X-124511)
Recommended Standards
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- Erdafitinib Impurity 2 (CAS 123342-12-1)
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- Ozagrel Impurity 12 (CAS 530145-11-0)
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- 4-Bromonicotinic acid hydrobromide (CAS 1794760-22-7)
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