3-Amino-4-methyl-6-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide CAS 255909-24-1
| CAS No. | 255909-24-1 |
| Molecular Formula | C10H8F3N3OS |
| Molecular Weight | 275.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-Amino-4-methyl-6-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 255909-24-1) is a high-purity analytical reference standard with the molecular formula C10H8F3N3OS and a molecular weight of 275.25 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution, 3-Amino-4-methyl-6-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 275.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 3-Amino-4-methyl-6-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8F3N3OS |
| Molecular Weight | 275.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Amino Standards
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Recommended Standards
- 3-[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]propanoic acid (CAS 885527-39-9)
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- 3,6-Dimethyl-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxylic acid (CAS 885461-44-9)
- 4-(difluoromethyl)-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-6-ol (CAS 832746-77-7)
- (2,2-Dimethylcyclobutyl)methanamine (CAS 1781332-45-3)
- (1S)-1-cyclopropyl-2,2,2-trifluoroethan-1-amine hydrochloride (CAS 1338377-73-3)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5,5-dimethylhexanoic acid (CAS 1217704-60-3)
- 1-{4-[(2,3-dihydro-1h-indol-1-yl)methyl]phenyl}methanamine (CAS 954260-60-7)
- Ethyl 6-iodoquinoline-3-carboxylate (CAS 1416440-20-4)
- 2-((Trimethylsilyl)ethynyl)phenol (CAS 81787-62-4)
- N-(3-Nitropyridin-2-yl)methanesulfonamide (CAS 1820716-87-7)
- 5-Chloro-2-(cyclopropylmethoxy)pyridine (CAS 1489543-49-8)
- 5-amino-6-methylpiperidin-2-one (CAS 1521412-60-1)
- (10-31)Semaglutide (CAS CATO-C4X-2226283)
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