5-Amino-6-(2,4-difluorophenoxy)-2,3-dihydro-1H-inden-1-one CAS 82505-55-3
| CAS No. | 82505-55-3 |
| Molecular Formula | C15H11F2NO2 |
| Molecular Weight | 275.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5-Amino-6-(2,4-difluorophenoxy)-2,3-dihydro-1H-inden-1-one (CAS 82505-55-3), a certified reference material (molecular formula C15H11F2NO2, MW 275.25 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 5-Amino-6-(2,4-difluorophenoxy)-2,3-dihydro-1H-inden-1-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 275.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H11F2NO2 |
| Molecular Weight | 275.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Amino Standards
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Recommended Standards
- 4-[4-(trifluoromethyl)phenyl]-3,5-thiomorpholinedione (CAS 338421-23-1)
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- 4-({[(thiophen-2-yl)methyl]amino}methylidene)-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-one (CAS 240115-98-4)
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- 2-(2,2-Dimethyl-1,3-dioxan-5-yl)ethan-1-ol (CAS 102147-75-1)
- Trichloro(3,3,4,4,5,5,6,6,6-nonafluorohexyl)silane (CAS 78560-47-1)
- (2R)-2-{[(tert-Butoxycarbonyl)amino]-methyl}-4,4-dimethylpentanoic acid (CAS 1355338-29-2)
- Valosin Peptide (VQY), porcine (CAS 99510-37-9)
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