2-{[4-(trifluoromethyl)-2-pyridyl]oxy}ethyl 4-methyl-1,2,3-thiadiazole-5-carboxylate CAS 257625-01-7
| CAS No. | 257625-01-7 |
| Molecular Formula | C12H10F3N3O3S |
| Molecular Weight | 333.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-{[4-(trifluoromethyl)-2-pyridyl]oxy}ethyl 4-methyl-1,2,3-thiadiazole-5-carboxylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-{[4-(trifluoromethyl)-2-pyridyl]oxy}ethyl 4-methyl-1,2,3-thiadiazole-5-carboxylate (CAS 257625-01-7) is a high-purity analytical reference standard with the molecular formula C12H10F3N3O3S and a molecular weight of 333.29 g/mol.
The molecular framework of 2-{[4-(trifluoromethyl)-2-pyridyl]oxy}ethyl 4-methyl-1,2,3-thiadiazole-5-carboxylate (C12H10F3N3O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-{[4-(trifluoromethyl)-2-pyridyl]oxy}ethyl 4-methyl-1,2,3-thiadiazole-5-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10F3N3O3S |
| Molecular Weight | 333.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related trifluoromethyl Standards
- 3-[[[1-Methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]carbonyl]amino]-2-thiophenecarboxylic Acid Methyl Ester (CAS 293326-85-9)
- Boc-2-(trifluoromethyl)-L-phenylalanine (CAS 167993-21-7)
- Ethyl 5-(4-(trifluoromethyl)phenyl)-1H-indole-2-carboxylate (CAS 871927-70-7)
- Methyl 1-(3-(trifluoromethyl)benzyl)-1H-indole-2-carboxylate (CAS 860785-06-4)
- N-(3-(trifluoromethyl)benzyl)-2H-chromene-3-carboxamide (CAS 338420-01-2)
- Bis({[3-(trifluoromethyl)phenyl]methyl})amine (CAS 863763-65-9)
- 1-Oxo-2-(4-(trifluoromethyl)phenyl)-1,2-dihydroisoquinoline-4-carboxylic acid (CAS 133096-33-0)
- 4-Oxo-3-(3-(trifluoromethyl)phenyl)-3,4-dihydrophthalazine-1-carboxamide (CAS 241127-33-3)
Recommended Standards
- 2-(3-Cyclopropyl-4-(difluoromethyl)-6-(furan-2-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid (CAS 937607-24-4)
- 2-((1-Methyl-1H-tetrazol-5-yl)thio)-N-(4-(trifluoromethoxy)phenyl)acetamide (CAS 212074-56-1)
- 4-(1,3-Dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)-2-hydroxybenzoic acid (CAS 55815-20-8)
- (4E)-2-(2,6-Difluorophenyl)-4-[1-(dimethylamino)-2-(1H-1,2,4-triazol-1-yl)ethylidene]-4,5-dihydro-1,3-oxazol-5-one (CAS 866010-31-3)
- 6-Amino-1-methyl-6,7,8,9-tetrahydro-11h-pyrido[2,1-b]quinazolin-11-one (CAS 1375474-03-5)
- 3-Fluoro-2-iodo-6-(trifluoromethyl)pyridine (CAS 1214359-56-4)
- 4-Fluoro-N'-(3-(pyridin-3-yl)-4,5-dihydroisoxazole-5-carbonyl)benzenesulfonohydrazide (CAS 478078-50-1)
- 4-Amino-1H-indazole-5-carboxylic acid (CAS 81115-63-1)
- Pyrrolidine-1,2-dicarboxylic acid 1-phenyl ester (CAS 1161602-22-7)
- FA-Asp-Ala-OH (CAS 196791-00-1)
- 5-Oxopyrrolidin-3-yl (3-chlorophenyl)carbamate (CAS 88015-87-6)
- 2-(2-Aminoethoxy)anisole D3 (CAS 1189881-28-4)
- 9-Octadecenoic acid (9Z)-, tin(2+) salt (2:1) (CAS 1912-84-1)
- Semaglutide Impurity 2 (CAS CATO-C4X-22262)
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