N-(3-(trifluoromethyl)benzyl)-2H-chromene-3-carboxamide CAS 338420-01-2
| CAS No. | 338420-01-2 |
| Molecular Formula | C18H14F3NO2 |
| Molecular Weight | 333.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(3-(trifluoromethyl)benzyl)-2H-chromene-3-carboxamide (CAS 338420-01-2), molecular formula C18H14F3NO2 and molecular weight 333.30 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(3-(trifluoromethyl)benzyl)-2H-chromene-3-carboxamide (C18H14F3NO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures N-(3-(trifluoromethyl)benzyl)-2H-chromene-3-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H14F3NO2 |
| Molecular Weight | 333.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- Boc-2-(trifluoromethyl)-L-phenylalanine (CAS 167993-21-7)
- Ethyl 5-(4-(trifluoromethyl)phenyl)-1H-indole-2-carboxylate (CAS 871927-70-7)
- Methyl 1-(3-(trifluoromethyl)benzyl)-1H-indole-2-carboxylate (CAS 860785-06-4)
- 2-{[4-(trifluoromethyl)-2-pyridyl]oxy}ethyl 4-methyl-1,2,3-thiadiazole-5-carboxylate (CAS 257625-01-7)
- 3-[[[1-Methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]carbonyl]amino]-2-thiophenecarboxylic Acid Methyl Ester (CAS 293326-85-9)
- Bis({[3-(trifluoromethyl)phenyl]methyl})amine (CAS 863763-65-9)
- 1-Oxo-2-(4-(trifluoromethyl)phenyl)-1,2-dihydroisoquinoline-4-carboxylic acid (CAS 133096-33-0)
- 4-Oxo-3-(3-(trifluoromethyl)phenyl)-3,4-dihydrophthalazine-1-carboxamide (CAS 241127-33-3)
Recommended Standards
- N-(2-(Benzofuran-3-yl)ethyl)-2-(trifluoromethyl)benzamide (CAS 920537-56-0)
- N-Boc-3-(trifluoromethyl)-D-phenylalanine (CAS 82317-82-6)
- Methyl 4-(2-(4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carbonyl)hydrazinyl)-4-oxobutanoate (CAS 300806-03-5)
- UBP 282 (CAS 544697-47-4)
- 4-Bromo-1-ethynyl-2-(trifluoromethyl)benzene (CAS 2244085-78-5)
- 6-Bromospiro[chromane-2,1'-cyclobutan]-4-one (CAS 934555-03-0)
- N-(azetidin-3-yl)-N-methylmethanesulfonamide; trifluoroacetic acid (CAS 1619991-24-0)
- 6-(2-Methoxyethoxy)benzo[d][1,3]dioxole-5-carbaldehyde (CAS 1209421-99-7)
- 4-Chloro-5-sulfamoylanthranilic Acid Methyl Ester (CAS 3994-89-6)
- Loxoprofen Impurity 48 (CAS 80530-54-7)
- Ethyl 5-isopropylisoxazole-3-carboxylate (CAS 91240-30-1)
- (2-Methoxy-1,4-phenylene)dimethanamine (CAS 119402-72-1)
- IP3(1,3,4) (CAS 1246355-66-7)
- Antistasin-Related Peptide (CAS 161561-46-2)
Why CATO?
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