Cabozantinib Impurity 14 CAS CATO-C4X-201814
| CAS No. | CATO-C4X-201814 |
| Molecular Formula | C22H27N4O3 |
| Molecular Weight | 395.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C22H27N4O3, Cabozantinib Impurity 14 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 395.47 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Cabozantinib Impurity 14 (CAS CATO-C4X-201814) is a certified pharmaceutical impurity reference standard with the molecular formula C22H27N4O3 and a molecular weight of 395.47 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H27N4O3 |
| Molecular Weight | 395.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Cabozantinib Standards
- Cabozantinib Impurity 15 (CAS 849217-77-2)
- Cabozantinib Impurity 18 (CAS CATO-C4X-201818)
- Cabozantinib Impurity N3 (CAS 651054-52-3)
- Cabozantinib Impurity 50 (CAS CATO-C4X-201850)
- Cabozantinib Impurity 23 (CAS CATO-C4X-201823)
- Cabozantinib Impurity 2 (CAS 190728-24-6)
- Cabozantinib Impurity 48 (CAS CATO-C4X-201848)
- Cabozantinib Impurity 3 (CAS 1431468-36-8)
Recommended Standards
- Ixazomib Impurity 18 (CAS CATO-C4X-126718)
- Lumateperone Impurity 50 (CAS 2117618-98-9)
- Ixazomib Impurity 17 (CAS CATO-C4X-126717)
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- Zolmitriptan Impurity 34 HCl (CAS 139264-57-6)
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