Paliperidone Impurity 50 CAS 260273-82-3
| CAS No. | 260273-82-3 |
| Molecular Formula | C11H11ClN2O2 |
| Molecular Weight | 238.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Paliperidone Impurity 50 (CAS 260273-82-3), a pharmacopoeial impurity reference standard (molecular formula C11H11ClN2O2, MW 238.67 g/mol) used for the identification and quantification of trace impurities in APIs.
Paliperidone Impurity 50 (C11H11ClN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H11ClN2O2 |
| Molecular Weight | 238.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Paliperidone Standards
- Paliperidone Impurity 103 (CAS CATO-C4X-1724103)
- Paliperidone Impurity 104 (CAS CATO-C4X-1724104)
- Paliperidone Impurity 56 (CAS CATO-C4X-172456)
- Paliperidone Impurity 58 (CAS CATO-C4X-172458)
- Paliperidone Impurity 7 (CAS CATO-C4X-17247)
- Paliperidone Impurity 78 (CAS 691007-05-3)
- Paliperidone Impurity 81 (CAS 691007-07-5)
- Paliperidone Impurity 61 (CAS 1138463-56-5)
Recommended Standards
- Tryptophan Impurity 46 (CAS 56632-86-1)
- 7-Chloro-L-Tryptophan (CAS 73945-46-7)
- Tryptophan Impurity 21 (CAS 55325-48-9)
- Ethychlozate (CAS 27512-72-7)
- Baclofen impurity 18 (CAS CATO-C4X-101218)
- Ketoconazole Impurity 17 (CAS 67914-60-7)
- Oxytocin Impurity 39 (CAS 1352167-71-5(free base))
- Ethyl 2-acetamido-3-(3,5-diiodo-4-(4-methoxyphenoxy)phenyl)propanoate (CAS 83249-56-3)
- (3-Fluoro-5-(trifluoromethoxy)phenyl)methanol (CAS 86256-47-5)
- cis-Cyclopentane-1,3-dicarboxylic acid (CAS 876-05-1)
- 4-Chloro-2-methyl-7-(trifluoromethyl)quinoline (CAS 18529-09-4)
- 1-(4-Nitrobenzylidene)-2-phenylhydrazine (CAS 2829-27-8)
- (E)-4-((3,4-dichlorobenzyl)oxy)-N'-(2-phenoxybenzylidene)benzohydrazide (CAS 303987-31-7)
- semaglutide (CAS 782487-28-9)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com