Baclofen impurity 18 CAS CATO-C4X-101218
| CAS No. | CATO-C4X-101218 |
| Molecular Formula | C11H13ClN2O2 |
| Molecular Weight | 240.69 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Baclofen impurity 18 (CAS CATO-C4X-101218), a pharmacopoeial impurity reference standard (molecular formula C11H13ClN2O2, MW 240.69 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C11H13ClN2O2, Baclofen impurity 18 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 240.69 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Baclofen impurity 18 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H13ClN2O2 |
| Molecular Weight | 240.69 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Baclofen Standards
- Baclofen Impurity 40 (CAS CATO-C4X-101240)
- Baclofen EP Impurity B (CAS 1141-23-7)
- Baclofen Impurity 37 (CAS CATO-C4X-101237)
- Baclofen Impurity 38 (CAS CATO-C4X-101238)
- Baclofen Impurity 41 (CAS 159156-84-0)
- Baclofen impurity 12 (CAS 232597-00-1)
- Baclofen EP Impurity C (CAS 35271-74-0)
- Baclofen impurity 7 (CAS 103857-58-5)
Recommended Standards
- 926228-16-2 N-(4-Amino-2-chlorophenyl)tetrahydro-2-furancarboxamide (CAS 926228-16-2)
- 3817AE 446848-52-8 C11H13ClN2O2 N-{4-[Acetyl(methyl)amino]phenyl}-2-chloroacetamide (CAS 446848-52-8)
- Paliperidone Impurity 61 (CAS 1138463-56-5)
- 1-(6-Chloro-3-pyridazinyl)-4-piperidinecarboxamide 303149-97-5 9571AD C10H13ClN4O (CAS 303149-97-5)
- Pidotimod Impurity 24 (CAS 161771-75-1)
- Fosaprepitant impurity 57（S,R,R） (CAS CATO-C4X-116857)
- Flomoxef Impurity 9 Sodium Sal (CAS 2095697-77-9 (free acid))
- (3Z)-N-(2,4-Dichlorophenyl)-3-(methoxyimino)propanamide (CAS 338976-60-6)
- 6,8-Difluoro-4-methoxyquinoline-2-carboxylic acid (CAS 1338651-82-3)
- Tert-butyl (R)-8-hydroxy-5-azaspiro[3.5]Nonane-5-carboxylate (CAS 2381925-50-2)
- (E)-N-(4-(2,4-dichlorophenyl)thiazol-2-yl)-1-(furan-2-yl)methanimine (CAS 866048-98-8)
- 1-Cyclobutyl-1H-pyrazole (CAS 1190875-37-6)
- (2S,3R,4S,5S,6R)-2-(4-Allylphenoxy)-6-((((2R,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)methyl)tetrahydro-2H-pyran-3,4,5-triol (CAS 499-33-2)
- Dulaglutide (CAS 923950-08-7)
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