2-(2,4-Difluoro-6-(methoxymethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane CAS 2641028-73-9
| CAS No. | 2641028-73-9 |
| Molecular Formula | C14H19BF2O4 |
| Molecular Weight | 300.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(2,4-Difluoro-6-(methoxymethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (C14H19BF2O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 2-(2,4-Difluoro-6-(methoxymethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2641028-73-9), a certified reference material (molecular formula C14H19BF2O4, MW 300.11 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H19BF2O4 |
| Molecular Weight | 300.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F-containing |
Related Difluoro Standards
- 2-(2,6-Difluoro-3,5-dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1614233-69-0)
- 3,5-Difluoro-2,4-dimethoxyiodobenzene (CAS 1208075-96-0)
- 2-(7,8-difluoro-1-naphthyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2454490-85-6)
- 2,4-Difluoro-3-(3,4,5-trifluorophenyl)-propiophenone (CAS 898778-62-6)
- 8-(2,6-Difluoro-4-nitrophenyl)-1,4-dioxa-8-azaspiro[4.5]decane (CAS 1332356-41-8)
- 2,6-Difluoro-N-[2-(1H-indol-3-yl)ethyl]benzamide (CAS 497060-52-3)
- 2,3-Difluoro-4-(Nonyloxy)Benzoic Acid (CAS 122265-97-8)
- 3,4-Difluoro-N-(4-((methylthio)methyl)thiazol-2-yl)benzamide (CAS 942009-60-1)
Recommended Standards
- Ethyl 2-(6-bromo-2-oxobenzo[d]oxazol-3(2H)-yl)acetate (CAS 176845-10-6)
- 2-(2-Bromo-4-cyano-6-ethoxyphenoxy)acetic acid (CAS 932843-98-6)
- 2-(3-(Difluoromethoxy)-4-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2092444-39-6)
- Spiro[1,3-dioxolane-2,1'-[1H]indene], 6'-bromo-2',3'-dihydro-5'-nitro- (CAS 158205-21-1)
- 3-Amino-N-(3,4-dimethoxybenzyl)-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide (CAS 664999-37-5)
- 2,5-Dimethyl-1-(1,3-thiazol-2-yl)-1h-pyrrole-3-carboxylic acid (CAS 953902-12-0)
- Piperidin-4-yl(pyridin-3-yl)methanone hydrochloride (CAS 1004529-41-2)
- (3-Aminopropyl)carbamic acid (CAS 94088-76-3)
- Methyl 2-({5-[1-(4-chlorophenyl)-4-oxo-1,4-dihydropyridazin-3-yl]-4-ethyl-4H-1,2,4-triazol-3-yl}sulfanyl)acetate (CAS 478077-62-2)
- 1-(2,4,6-trifluorophenyl)piperazine (CAS 759443-28-2)
- 4-Methyl-N-(thiophen-3-ylmethyl)pyridin-3-amine (CAS 1340521-62-1)
- 1-[(2-methylpiperidin-1-yl)sulfonyl]piperazine (CAS 923208-46-2)
- 4-Hydroxy-N,N-dimethylnicotinamide (CAS 1055935-42-6)
- endo-Gly31-Semaglutide (CAS CATO-C4X-2226282)
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