2,6-Difluoro-N-[2-(1H-indol-3-yl)ethyl]benzamide CAS 497060-52-3
| CAS No. | 497060-52-3 |
| Molecular Formula | C17H14F2N2O |
| Molecular Weight | 300.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,6-Difluoro-N-[2-(1H-indol-3-yl)ethyl]benzamide (CAS 497060-52-3) is a high-purity analytical reference standard with the molecular formula C17H14F2N2O and a molecular weight of 300.30 g/mol.
Based on its molecular formula C17H14F2N2O, 2,6-Difluoro-N-[2-(1H-indol-3-yl)ethyl]benzamide contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 300.30 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H14F2N2O |
| Molecular Weight | 300.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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- 3,4-Difluoro-N-(4-((methylthio)methyl)thiazol-2-yl)benzamide (CAS 942009-60-1)
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- 2-(2,6-Difluoro-3,5-dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1614233-69-0)
- 2-(2,4-Difluoro-6-(methoxymethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2641028-73-9)
- 3,5-Difluoro-2,4-dimethoxyiodobenzene (CAS 1208075-96-0)
Recommended Standards
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- 2-(Ethylthio)-3-(2-(trifluoromethyl)phenyl)pyrimidin-4(3H)-one (CAS 89069-56-7)
- 4-(4-Methylphenoxy)-2-(methylsulfanyl)-6-(trifluoromethyl)pyrimidine (CAS 477856-00-1)
- N-(2-(Dimethylamino)-2-(thiophen-2-yl)ethyl)-4-methylbenzenesulfonamide (CAS 941977-59-9)
- Galanthaminone (hydrobromide) (CAS 690959-38-7)
- 4-(M-tolyl)piperazine-1-carboximidamide (CAS 17238-62-9)
- 5-Amino-3-(ethoxymethyl)-1-ethylpyrimidine-2,4(1h,3h)-dione (CAS 1495295-93-6)
- 5-Bromo-7,7-dimethyl-7H-benzo[c]fluorene (CAS 954137-48-5)
- 2-((3-Methylbenzyl)amino)butan-1-ol (CAS 1042623-01-7)
- tert-Butyl (4-iodo-2-methoxyphenyl)carbamate (CAS 876346-94-0)
- [(1-methyl-1H-pyrazol-4-yl)methyl](propyl)amine (CAS 1152839-68-3)
- 3-(4,6-Dichloro-1,3,5-triazin-2-yl)-1-phenyl-1H-indole (CAS 35252-64-3)
- Semaglutide impurity 46 (CAS CATO-C4X-222646)
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