Ethyl 3-(6-chloroimidazo[2,1-b]thiazol-5-yl)-2-cyanoacrylate CAS 265307-86-6
| CAS No. | 265307-86-6 |
| Molecular Formula | C11H8ClN3O2S |
| Molecular Weight | 281.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl 3-(6-chloroimidazo[2,1-b]thiazol-5-yl)-2-cyanoacrylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ethyl 3-(6-chloroimidazo[2,1-b]thiazol-5-yl)-2-cyanoacrylate (CAS 265307-86-6) is a high-purity analytical reference standard with the molecular formula C11H8ClN3O2S and a molecular weight of 281.72 g/mol.
Structurally, Ethyl 3-(6-chloroimidazo[2,1-b]thiazol-5-yl)-2-cyanoacrylate (C11H8ClN3O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 281.72 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Ethyl 3-(6-chloroimidazo[2,1-b]thiazol-5-yl)-2-cyanoacrylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H8ClN3O2S |
| Molecular Weight | 281.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Ethyl Standards
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Recommended Standards
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- N-Cbz-piperidine-4-carbonyl Chloride (CAS 10314-99-5)
- 3-Chloro-6-methoxy-1-methyl-1H-indole-2-carboxylic acid (CAS 1355179-52-0)
- 3-Chloro-2-naphthoic acid (CAS 19411-56-4)
- 2,4-dichloro-6-fluoropyrrolo[2,1-f][1,2,4]triazine (CAS 2306276-28-6)
- 3-Bromo-4-methoxyphenylboronic acid pinacol ester (CAS 1394130-69-8)
- L-Glutamic acid diallyl ester (tosylate) (CAS 20845-16-3)
- 2-(2-(1H-Benzo[d]imidazol-2-yl)ethyl)-N-(2-chlorophenyl)hydrazinecarbothioamide (CAS 78772-46-0)
- 1-(4-aminophenyl)guanidine dihydrochloride (CAS 951323-36-7)
- N-(imidazo[1,2-a]pyridin-2-ylmethyl)tetrahydro-2H-pyran-4-amine (CAS 1153229-37-8)
- 4-(2-Furyl)-2-hydrazino-1,3-thiazole (CAS 21036-64-6)
- Semaglutide Impurity 142 (CAS CATO-C4X-2226142)
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