Mesalazine Impurity 2 CAS 26537-19-9
| CAS No. | 26537-19-9 |
| Molecular Formula | C12H16O2 |
| Molecular Weight | 192.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Mesalazine Impurity 2 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Mesalazine Impurity 2 (CAS 26537-19-9, C12H16O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Mesalazine Impurity 2 (C12H16O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 192.25 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C12H16O2 |
| Molecular Weight | 192.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
Related Mesalazine Standards
- Mesalazine Impurity 21 (CAS 51-59-2)
- Mesalazine Impurity 24 (CAS 859964-08-2)
- Mesalazine Impurity 26 (CAS 1689-82-3)
- Mesalazine Impurity 27 (CAS 2362-57-4)
- Mesalazine Impurity 29 (CAS 2437-11-8)
- Mesalazine EP Impurity N (CAS 96-97-9)
- Mesalazine EP Impurity R (CAS 85-38-1)
- Mesalazine EP Impurity M (CAS 2516-96-3)
Recommended Standards
- Mirogabalin Impurity 97 (CAS CATO-C4X-292497)
- Tripropylene Glycol (mixture of isomers) (CAS 24800-44-0)
- Mirogabalin Impurity 184 (CAS CATO-C4X-2924184)
- Isovaleric acid-benzyl ester (CAS 103-38-8)
- N-Nitroso Flupirtine Dimer Impurity 10 (CAS CATO-C4X-104210)
- Lorazepam Impurity 11 (CAS CATO-C4X-104111)
- Lornoxicam Impurity 97 (CAS CATO-C4X-201697)
- 6-(Chloromethyl)-4-(4-methoxybenzyl)morpholin-3-one (CAS 1033201-59-0)
- Amlodipine maleate (CAS 88150-47-4)
- Isotretinoin EP Impurity G (5,6-Epoxy-13-cis Retinoic Acid) (and enantiomer) (CAS 81444-57-7)
- 4-Bromo-3-nitro-1-(tetrahydrofuran-3-yl)-1H-pyrazole (CAS 1340409-03-1)
- 8-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-3,3-dimethyl-N-phenyl-1,4,8-triazaspiro[4.5]Decane-1-carboxamide (CAS 338761-60-7)
- Methyl spiro[2.3]Hexane-4-carboxylate (CAS 2122560-72-7)
- Tripeptide-10 citrulline (CAS 960531-53-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com