Mesalazine EP Impurity R CAS 85-38-1
| CAS No. | 85-38-1 |
| Molecular Formula | C7H5NO5 |
| Molecular Weight | 183.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Mesalazine EP Impurity R.
As a process- or degradation-related impurity, Mesalazine EP Impurity R (CAS 85-38-1, C7H5NO5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Mesalazine EP Impurity R (C7H5NO5) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Mesalazine EP Impurity R meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5NO5 |
| Molecular Weight | 183.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Mesalazine Standards
- Mesalazine EP Impurity N (CAS 96-97-9)
- Mesalazine Impurity 43 (CAS 616-79-5)
- Mesalazine Impurity 56 (CAS CATO-C4X-132456)
- Mesalazine Ethyl Ester (CAS 62773-65-3)
- Mesalazine Impurity 42 (CAS 104786-99-4)
- Mesalazine Impurity 3 (CAS 98-73-7)
- Mesalazine Impurity 2 (CAS 26537-19-9)
- Mesalazine Impurity 21 (CAS 51-59-2)
Recommended Standards
- Entacapone EP Impurity C(Mixtures of tautomers) (CAS 116313-85-0)
- 4-Hydroxy-3-nitrobenzoic acid (CAS 616-82-0)
- Indocyanine Green Impurity 15 (2,4-Dinitroaniline) (CAS 97-02-9)
- 1,8-Dichlorooctane 2162-99-4 D1012 Octamethylene Chloride Octamethylene Dichloride (CAS 2162-99-4)
- Lifitegrast Impurity 151 (CAS CATO-C4X-2409151)
- Etonogestrel Impurity 2 (CAS 946163-50-4)
- Finerenone Impurity 195 (CAS CATO-C4X-2880195)
- 5-Bromo-2-methyl-3-sulfamoylbenzoic acid (CAS 1375472-31-3)
- 3,5,6,7-tetrahydro-4H-Cyclopentapyrimidin-4-one (CAS 5661-01-8)
- 1187169-96-5 4-(5-Chloro-2-thienyl)-2-methylpyridine MFCD13152436 (CAS 1187169-96-5)
- N-(4-Acetylphenyl)-4-bromo-3-nitrobenzamide (CAS 1286050-26-7)
- {[4-(2-Methylpropyl)phenyl]methyl}(propyl)amine hydrochloride (CAS 1240566-81-7)
- 5-Bromo-N-(3-chloro-4-fluorophenyl)-2-hydroxybenzamide (CAS 663152-26-9)
- (D-His1)-Exenatide trifluoroacetate salt (CAS 1678417-09-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com