N'1-[(2-chloro-6-methylpyrimidin-4-yl)carbonyl]-2-(trifluoromethoxy)benzene-1-carbohydrazide CAS 266337-54-6
| CAS No. | 266337-54-6 |
| Molecular Formula | C14H10ClF3N4O3 |
| Molecular Weight | 374.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N'1-[(2-chloro-6-methylpyrimidin-4-yl)carbonyl]-2-(trifluoromethoxy)benzene-1-carbohydrazide.
N'1-[(2-chloro-6-methylpyrimidin-4-yl)carbonyl]-2-(trifluoromethoxy)benzene-1-carbohydrazide (CAS 266337-54-6), molecular formula C14H10ClF3N4O3 and molecular weight 374.70 g/mol, is a CATO reference standard with documented purity and traceability.
N'1-[(2-chloro-6-methylpyrimidin-4-yl)carbonyl]-2-(trifluoromethoxy)benzene-1-carbohydrazide (C14H10ClF3N4O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N'1-[(2-chloro-6-methylpyrimidin-4-yl)carbonyl]-2-(trifluoromethoxy)benzene-1-carbohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H10ClF3N4O3 |
| Molecular Weight | 374.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
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- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(3,5-dimethoxyphenyl)acetamide (CAS 477890-09-8)
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Recommended Standards
- Benzyl 6-aminohexanoate 4-methylbenzenesulfonate (CAS 5514-99-8)
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- Econazole impurity 25 (CAS CATO-C4X-132725)
- [(2R,3S,4R,5R)-5-(6-chloropurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate (CAS 5843-59-4)
- 1,1-Diphenylbutan-2-one (CAS 6336-52-3)
- 4-Fluoro-9-(((trifluoromethyl)sulfonyl)oxy)-6,7-dihydro-5H-benzo[7]annulen-3-yl pivalate (CAS 2114341-49-8)
- 2,6-Dichloro-3-(bromomethyl)pyridine (CAS 58596-59-1)
- 6-(Dimethoxymethyl)-5-(trifluoromethyl)pyridine-3-sulfonyl chloride (CAS 2851879-18-8)
- 4-(((3-Hydroxy-1-oxo-1H-inden-2-yl)methylene)amino)-N-(pyrimidin-2-yl)benzenesulfonamide (CAS 497061-23-1)
- Hexarelin (CAS 140703-51-1)
- 3-(2-Bromo-4-fluoro-phenyl)-acrylic acid methyl ester (CAS 404575-30-0)
- N-(n-Nonyl)deoxygalactonojirimycin (CAS 223771-83-3)
- (R)-2-Ethylcyclopentanone (CAS 71049-87-1)
- (Pro3)-Gastric Inhibitory Polypeptide (human) trifluoroacetate salt (CAS 299898-52-5)
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