2-[(3-Chloro-4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)carbamoyl]acetic acid CAS 321433-62-9
| CAS No. | 321433-62-9 |
| Molecular Formula | C15H10ClF3N2O4 |
| Molecular Weight | 374.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-[(3-Chloro-4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)carbamoyl]acetic acid (CAS 321433-62-9) is a high-purity analytical reference standard with the molecular formula C15H10ClF3N2O4 and a molecular weight of 374.70 g/mol.
The molecular framework of 2-[(3-Chloro-4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)carbamoyl]acetic acid (C15H10ClF3N2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 2-[(3-Chloro-4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)carbamoyl]acetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H10ClF3N2O4 |
| Molecular Weight | 374.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
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Recommended Standards
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- 5857-45-4 3-methylimidazo[1,2-a]pyridine DTXSID30481500 (CAS 5857-45-4)
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- 1-(Thiophen-3-yl)hexan-1-amine (CAS 1250162-20-9)
- Insulin degludec (CAS 844439-96-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com