Timolol EP Impurity A Maleate CAS 26839-77-0
| CAS No. | 26839-77-0 |
| Molecular Formula | C13H24N4O3S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 432.49 g/mol gives Timolol EP Impurity A Maleate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Timolol EP Impurity A Maleate (CAS 26839-77-0) is a certified pharmaceutical impurity reference standard with the molecular formula C13H24N4O3SC4H4O4 and a molecular weight of 432.49 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Timolol EP Impurity A Maleate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 432.49 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Timolol EP Impurity A Maleate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H24N4O3S C4H4O4 |
| Molecular Weight | 432.49 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Timolol Standards
- Timolol EP Impurity E (CAS 1026075-53-5)
- Timolol EP Impurity C (CAS 1391068-18-0)
- Timolol EP Impurity B（S-Isomer) (CAS 158636-96-5)
- Timolol EP Impurity H (CAS 158636-97-6)
- r-tImolol 2-butenedioate (CAS 1820576-27-9)
- Timolol Impurity 16 (CAS 214691-24-4)
- Timolol EP Impurity I (CAS 2469037-77-0)
- Timolol (CAS 26839-75-8)
Recommended Standards
- Budesonide Impurity 77 (CAS CATO-C4X-138977)
- Esomeprazole Impurity 85 (CAS CATO-C4X-111285)
- Nafamostat impurity 79 (CAS 838873-15-7)
- 5-Bromo-2-(4-methylpiperazin-1-yl)pyridin-3-amine (CAS 1226389-57-6)
- 6-Hydroxy-5-iodonicotinonitrile (CAS 1135283-36-1)
- 2-{[4-(4-methylphenyl)-6-(trifluoromethyl)pyrimidin-2-yl]oxy}ethan-1-amine (CAS 1160246-50-3)
- 2-(Dimethylamino)-2-methylpropanenitrile (CAS 2273-40-7)
- 1,2-Propanediol, polymer with N1-(2-aminoethyl)-1,2-ethanediamine (CAS 68492-63-7)
- trans-4-((4-(1-Phenyl-1H-pyrazol-4-yl)pyrimidin-2-yl)amino)cyclohexanol (CAS 1212419-99-2)
- 107444-51-9 0JS9125PIZ Glucagon-like peptide 1 (7-36) Glucagon-related peptide 1 (Rana catesbeiana), 3-L-glutamic acid-10-L-valine-16-glycine-17-L-glutamine-23-L-isoleucine-24-L-alanine-27-L-valine-30-L-argininamide-31-de-L-proline-32-de-L-lysine- Glp-I (7-36) Proglucagon (78-107) Human glucagon-like peptide-1-(7-36) amide Human GLP-1-(7-36)-amide Glucagon-like peptide-I(7-36) amide Rat GLP-I(7-36)amide Insulinotropin (human) MKC 253 UNII-0JS9125PIZ (CAS 107444-51-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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