Benzbromarone Impurity 8 CAS 27003-05-0
| CAS No. | 27003-05-0 |
| Molecular Formula | C7H3Br2ClO2 |
| Molecular Weight | 314.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Benzbromarone Impurity 8 (CAS 27003-05-0) is a certified pharmaceutical impurity reference standard with the molecular formula C7H3Br2ClO2 and a molecular weight of 314.36 g/mol.
The molecular framework of Benzbromarone Impurity 8 (C7H3Br2ClO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Benzbromarone Impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H3Br2ClO2 |
| Molecular Weight | 314.36 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl/Br-containing |
Related Benzbromarone Standards
- Benzbromarone Impurity 14 (CAS 77823-55-3)
- Benzbromarone Impurity 18 (CAS 857537-46-3)
- Benzbromarone EP Impurity A (CAS 94729-09-6)
- Benzbromarone Impurity 12 (CAS 3343-80-4)
- Benzbromarone Impurity 23 (CAS CATO-C4X-225023)
- Benzbromarone Impurity 24 (CAS 342415-01-4)
- Benzbromarone Impurity 25 (CAS CATO-C4X-225025)
- Benzbromarone Impurity 32 (CAS CATO-C4X-225032)
Recommended Standards
- Sulfacarbamide Impurity 2 (CAS 526-08-9)
- 4,5-Dibromo-2-chlorobenzoic acid (CAS CATO-C4X-20757)
- Rofecoxib (CAS 162011-90-7)
- Parecoxib sodium Impurity 9 (CAS 1373038-56-2)
- Flecainide Impurity 8 (CAS CATO-C4X-25468)
- Propofol Impurity 35 (CAS 2215-21-6)
- Roxadustat Impurity 116 (CAS CATO-C4X-2213116)
- 5-Amino-1,2-dimethyl-1h-imidazole-4-carboxamide (CAS 78750-93-3)
- 3-(Difluoromethyl)-5-fluoro-4-methoxypyridin-2-amine (CAS 1805114-00-4)
- 1,3-dihydrospiro[indene-2,2’-pyrrolidine] (CAS 781559-69-1)
- 3-((6,7,8,9-Tetrahydro-5h-[1,2,4]triazolo[4,3-a]azepin-3-yl)thio)propanamide (CAS 1211785-76-0)
- 4'-Chloro-2'-fluoro-[1,1'-biphenyl]-3-carbaldehyde (CAS 1242339-63-4)
- 1-(2-Methyl-6-(trifluoromethyl)pyrimidin-4-yl)pyrrolidine-3-carboxylic acid (CAS 1707372-78-8)
- Semaglutide impurity 55 (CAS CATO-C4X-222655)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com