Propofol Impurity 35 CAS 2215-21-6
| CAS No. | 2215-21-6 |
| Molecular Formula | C13H18O3 |
| Molecular Weight | 222.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Propofol Impurity 35 (C13H18O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies Propofol Impurity 35 (CAS 2215-21-6), a pharmacopoeial impurity reference standard (molecular formula C13H18O3, MW 222.28 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Propofol Impurity 35 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H18O3 |
| Molecular Weight | 222.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Propofol Standards
- Propofol Impurity 21 (CAS 153752-00-2)
- Propofol EP Impurity N (CAS 13423-73-9)
- Propofol Impurity 32 (CAS 161070-01-5)
- Propofol Impurity 33 (CAS CATO-C4X-147333)
- Propofol Impurity 39 (CAS 100482-27-7)
- Propofol Impurity 46 (CAS CATO-C4X-147346)
- Propofol Impurity 48 (CAS CATO-C4X-147348)
- Propofol Impurity 59 (CAS CATO-C4X-147359)
Recommended Standards
- Glipizide Impurity 37 (CAS 350983-37-8)
- Sunitinib Impurity 13 (CAS 1309935-09-8)
- Propofol Impurity 60 (CAS CATO-C4X-147360)
- Aclidinium bromide Impurity 2 (CAS 7333-07-5)
- Trametinib Impurity 19 (CAS CATO-C4X-278219)
- Carbamazepine Impurity 15 (CAS CATO-C4X-118115)
- Diosmin Impurity 8 (Mixture of Diastereomers) (CAS 108815-81-2)
- 4-Hydroxy-2,7-bis(trifluoromethyl)quinoline-3-carboxylic acid (CAS 75999-57-4)
- 10-Methylphenothiazine (CAS 1207-72-3)
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- (2-Chloro-4-(m-tolylcarbamoyl)phenyl)boronic acid (CAS 2096338-25-7)
- Bimatoprost Impurity 2 (CAS 41639-74-1)
- 6-Bromo-5-(difluoromethyl)-4-hydroxynicotinaldehyde (CAS 1805349-45-4)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com