Flunarizine EP Impurity B DiHCl CAS 27064-96-6
| CAS No. | 27064-96-6 |
| Molecular Formula | C26H27FN2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Flunarizine EP Impurity B DiHCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Flunarizine EP Impurity B DiHCl (CAS 27064-96-6) is a certified pharmaceutical impurity reference standard with the molecular formula C26H27FN2HCl and a molecular weight of 422.97 g/mol.
The molecular framework of Flunarizine EP Impurity B DiHCl (C26H27FN2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C26H27FN2 2*HCl |
| Molecular Weight | 422.97 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Flunarizine Standards
- Flunarizine impurity 43 (CAS 1133842-25-7)
- Flunarizine Impurity 59 (CAS 114312-65-1)
- Flunarizine impurity 57 (CAS 114374-24-2)
- Flunarizine Impurity N1 (CAS 123375-94-0)
- Flunarizine Impurity N1 HCl (CAS 123375-94-0(free base))
- Flunarizine impurity 46 (CAS 1368426-98-5(free base))
- Flunarizine Impurity 32 (CAS 141528-78-1)
- Flunarizine Impurity 26 (CAS 144917-53-3)
Recommended Standards
- Belumosudil Impurity 68 (CAS CATO-C4X-298868)
- Cetilistat Impurity 6 (CAS 2302616-95-9)
- Tribenoside EP Impurity A (CAS 53928-30-6)
- 7,8-Difluoro-2-methoxyquinoline-4-carboxylic acid (CAS 1125702-51-3)
- 2-Isopropyl-1H-pyrazolo[1,5-b][1,2,4]triazole (CAS 197355-52-5)
- 2-Amino-5-(4-methoxyphenyl)-5,6-dihydrobenzo[d]thiazol-7(4H)-one (CAS 334506-30-8)
- 4-{3-[(2,6-dichlorophenyl)methyl]-2-methyl-4-oxo-1,4-dihydropyridin-1-yl}butanoic acid (CAS 400736-52-9)
- 2-Chloro-3-methoxypyridine-4-carboxylic acid (CAS 1214344-24-7)
- 2-(Trifluoromethyl)-7-azaspiro[3.5]nonan-2-ol (CAS 1251922-79-8)
- Semaglutide Impurity 163 (x TFA Salt) (CAS CATO-C4X-2226163)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com