Etoricoxib Impurity 46 CAS 2708988-48-9
| CAS No. | 2708988-48-9 |
| Molecular Formula | C18H16N2O3S |
| Molecular Weight | 340.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Etoricoxib Impurity 46 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Etoricoxib Impurity 46 (CAS 2708988-48-9), a pharmacopoeial impurity reference standard (molecular formula C18H16N2O3S, MW 340.40 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Etoricoxib Impurity 46 (C18H16N2O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C18H16N2O3S |
| Molecular Weight | 340.40 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Etoricoxib Standards
- Etoricoxib Impurity 52 (CAS CATO-C4X-108052)
- Etoricoxib Impurity 81 (CAS 2241145-66-2)
- Etoricoxib Impurity 84 (CAS CATO-C4X-108084)
- Etoricoxib Impurity 11 (CAS 2901801-70-3)
- Etoricoxib Impurity 2 (CAS 316149-01-6)
- Etoricoxib Impurity 83 (CAS CATO-C4X-108083)
- Etoricoxib Impurity 9 (CAS 202409-31-2)
- Etoricoxib Impurity 25 (CAS CATO-C4X-108025)
Recommended Standards
- (5E)-5-(2,4-Dimethoxybenzylidene)-2-mercapto-3-phenyl-3,5-dihydro-4H-imidazol-4-one 402608-16-6 (CAS 402608-16-6)
- Tris(4-vinylphenyl)phosphane (CAS 95705-40-1)
- Abrocitinib Impurity 12 (CAS CATO-C4X-288412)
- S-(5')-Adenosyl-3-thiopropylamine (CAS 53186-57-5)
- Regorafenib Impurity 58 (CAS 103842-00-8)
- Tofacitinib Impurity 177 (CAS CATO-C4X-1079177)
- Omeprazole Impurity 42 (CAS CATO-C4X-125542)
- 4-Amino-6-phenyl-2-(phenylamino)pyrimidine-5-carbonitrile (CAS 118965-88-1)
- 6-Chloro-2-hydroxy-3-methylbenzaldehyde (CAS 1310800-53-3)
- (3-Methyl-1-piperidinyl)(2-pyrrolidinyl)methanonehydrochloride (CAS 1246172-33-7)
- 2-(Chloromethyl)-1-fluoro-4-(trifluoromethoxy)benzene (CAS 1517586-69-4)
- 3-methyl-3-phenylcyclopentan-1-one (CAS 53750-06-4)
- 1-[[(2',3',6',7',12',13',16',17'-Octahydro-3-oxospiro[isobenzofuran-1(3H),9'-[1H,5H,9H,11H,15H]xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin]-6-yl)carbonyl]oxy]-2,5-pyrrolidinedione (CAS 117491-83-5)
- Semaglutide Main Chain P29 (CAS 1169630-82-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com