Venlafaxine Impurity 76 CAS CATO-C4X-143476
| CAS No. | CATO-C4X-143476 |
| Molecular Formula | C24H30ClNO3 |
| Molecular Weight | 415.95 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Venlafaxine Impurity 76 (CAS CATO-C4X-143476), a pharmacopoeial impurity reference standard (molecular formula C24H30ClNO3, MW 415.95 g/mol) used for the identification and quantification of trace impurities in APIs.
Venlafaxine Impurity 76 (C24H30ClNO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Venlafaxine Impurity 76 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H30ClNO3 |
| Molecular Weight | 415.95 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Venlafaxine Standards
- Venlafaxine Impurity N2 (CAS 1346601-14-6)
- Venlafaxine Impurity 68 (CAS CATO-C4X-143468)
- Venlafaxine EP Impurity H（Mixture of Enantiomers） (CAS 1329795-88-1)
- Venlafaxine Impurity 70 (CAS CATO-C4X-143470)
- Venlafaxine Impurity 13 (CAS CATO-C4X-143413)
- Venlafaxine impurity 56 (CAS 916918-81-5)
- Venlafaxine Impurity 11 (CAS CATO-C4X-143411)
- Venlafaxine Impurity 12 (CAS CATO-C4X-143412)
Recommended Standards
- 4-Formyl-2,6-diiodophenyl acetate (CAS 52273-39-9)
- 2-((4-Allyl-5-((phenylthio)methyl)-4H-1,2,4-triazol-3-yl)thio)-1-(4-chlorophenyl)ethanone (CAS 538337-57-4)
- 2-(4-Dibromomethylphenyl)hexafluoropropan-2-ol (CAS 1800567-68-3)
- Rupatadine impurity 12 (CAS CATO-C4X-102712)
- Travoprost Impurity 9 (CAS 22897-99-0)
- Bilastine impurity 87 (CAS 2890196-78-6（free base）)
- Selegiline EP Impurity D HCl (CAS 115586-38-4)
- 3-((Cyclohexylthio)methyl)piperidine (CAS 1248321-17-6)
- Dimethyliodoarsine (CAS 676-75-5)
- 4-(Benzyloxy)benzenesulfonic acid (CAS 5950-16-3)
- Benzo[de]chromen-2(3H)-one (CAS 3812-99-5)
- 2,4-Dichloro-3,5-Dinitrobenzonitrile (CAS 1930-71-8)
- Pitolisant impurity 30 (CAS CATO-C4X-252030)
- Neuropeptide GE (CAS 134748-04-2)
Why CATO?
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com