Iohexol EP Impurity B CAS 2732209-64-0
| CAS No. | 2732209-64-0 |
| Molecular Formula | C22H32I3N3O11 |
| Molecular Weight | 895.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Iohexol EP Impurity B is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Iohexol EP Impurity B (CAS 2732209-64-0) is a certified pharmaceutical impurity reference standard with the molecular formula C22H32I3N3O11 and a molecular weight of 895.22 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution, Iohexol EP Impurity B is typically off-white to pale yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 895.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H32I3N3O11 |
| Molecular Weight | 895.22 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 3 |
Related Iohexol Standards
- Iohexol EP Impurity C (CAS CATO-C4X-16643)
- Iohexol EP Impurity D (CAS 157739-09-8)
- Iohexol EP Impurity E (CAS 2727061-52-9)
- Iohexol Impurity 50 (CAS CATO-C4X-166450)
- Iohexol Impurity 28 (CAS 92339-10-1)
- Iohexol EP Impurity N (CAS CATO-C4X-166410)
- Iohexol EP Impurity O (CAS CATO-C4X-166411)
- Iohexol EP Impurity P (CAS CATO-C4X-166412)
Recommended Standards
- rel-6,6'-(((1R,1'R)-Ethane-1,2-diylbis(phenylphosphinediyl))bis(methylene))bis(4-(tert-butyl)-2-((1r,3R,5S,7R)-3,5-dimethyladamantan-1-yl)phenol) (CAS 1541178-73-7)
- Al (III) Phthalocyanine Chloride Tetrasulfonic Acid (CAS 100180-30-1)
- Palladium tetrakis(4-carboxyphenyl)porphyrin (CAS 94288-44-5)
- 4,4’,4’’,4’’’,4’’’’,4’’’’’-[[Ethane-1,1,1-triyltris(benzene-4,1-diyl)]tris(ethane-1,1,1-triyl)]hexaphenol (CAS 1010447-10-5)
- Nicardipine Impurity 49 (CAS CATO-C4X-171049)
- Flupirtine Impurity 2 (CAS 33400-49-6)
- Revefenacin impurity 32 (CAS CATO-C4X-203132)
- 4-(3-Methylphenazin-2-yl)morpholine (CAS 61155-57-5)
- 2-Methyl-3-((tetrahydro-2h-pyran-4-yl)methoxy)propane-1-sulfonyl chloride (CAS 1341477-90-4)
- Hexanenitrile (CAS 628-73-9)
- N-((4-(3-Chlorophenyl)-5-(methylthio)-4H-1,2,4-triazol-3-yl)methyl)-3-fluorobenzamide (CAS 391899-74-4)
- N-(4-((4-Hydroxy-9,10-dioxo-9,10-dihydroanthracen-1-yl)amino)phenyl)acetamide (CAS 67905-17-3)
- 2,5-Dichloro-3-(difluoromethoxy)benzoic acid (CAS 1806275-57-9)
- Tirzepatide Impurity 43 (CAS CATO-C4X-324043)
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