Iohexol EP Impurity N CAS CATO-C4X-166410
| CAS No. | CATO-C4X-166410 |
| Molecular Formula | C21H28I3N3O10 |
| Molecular Weight | 863.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Iohexol EP Impurity N (CAS CATO-C4X-166410, C21H28I3N3O10) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Iohexol EP Impurity N (C21H28I3N3O10) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Iohexol EP Impurity N under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H28I3N3O10 |
| Molecular Weight | 863.17 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | I-containing |
| Nitrogen Atoms | 3 |
Related Iohexol Standards
- Iohexol EP Impurity O (CAS CATO-C4X-166411)
- Iohexol EP Impurity P (CAS CATO-C4X-166412)
- Iohexol EP Impurity Q (CAS CATO-C4X-166413)
- Iohexol EP Impurity B (CAS 2732209-64-0)
- Iohexol EP Impurity C (CAS CATO-C4X-16643)
- Iohexol EP Impurity D (CAS 157739-09-8)
- Iohexol EP Impurity E (CAS 2727061-52-9)
- Iohexol Impurity 50 (CAS CATO-C4X-166450)
Recommended Standards
- 1-(3-(N-(2,3-Dihydroxypropyl)acetamido)-5-((2,3-dihydroxypropyl)carbamoyl)-2,4,6-triiodobenzamido)-3-hydroxypropan-2-yl acetate (Iodixanol Impurity) (CAS 2730989-02-1)
- (3AR,3'aS,3''aR,3'''aR,3''''aR,8aR,8'aS,8''aR,8'''aR,8''''aR)-1,1',1'',1''',1''''-pentamethyl-2,2',2'',2''',2'''',3,3',3'',3''',3'''',8,8a,8',8'a,8'',8''a,8''',8'''a,8'''',8''''a-icosahydro-1H,1'H,1''H,1'''H,1''''H-3a,7':3'a,3''a:7'',3'''a:7''',3''''a-quinquepyrrolo[2,3-b]indole (CAS 52617-25-1)
- Fmoc-Phe-Lys(Trt)-PAB (CAS 1116085-98-3)
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- 5-Amino-N,1-diphenyl-1H-pyrazole-4-carboxamide (CAS 497161-22-5)
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- Fmoc-Val-Ala-PAB-PNP (CAS 1394238-92-6)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com