Iohexol EP Impurity O CAS CATO-C4X-166411
| CAS No. | CATO-C4X-166411 |
| Molecular Formula | C21H28I3N3O10 |
| Molecular Weight | 863.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Iohexol EP Impurity O.
As a process- or degradation-related impurity, Iohexol EP Impurity O (CAS CATO-C4X-166411, C21H28I3N3O10) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Iohexol EP Impurity O (C21H28I3N3O10) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Iohexol EP Impurity O under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H28I3N3O10 |
| Molecular Weight | 863.17 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | I-containing |
| Nitrogen Atoms | 3 |
Related Iohexol Standards
- Iohexol EP Impurity N (CAS CATO-C4X-166410)
- Iohexol EP Impurity P (CAS CATO-C4X-166412)
- Iohexol EP Impurity Q (CAS CATO-C4X-166413)
- Iohexol EP Impurity B (CAS 2732209-64-0)
- Iohexol EP Impurity C (CAS CATO-C4X-16643)
- Iohexol EP Impurity D (CAS 157739-09-8)
- Iohexol EP Impurity E (CAS 2727061-52-9)
- Iohexol Impurity 50 (CAS CATO-C4X-166450)
Recommended Standards
- 1-(3-(N-(2,3-Dihydroxypropyl)acetamido)-5-((2,3-dihydroxypropyl)carbamoyl)-2,4,6-triiodobenzamido)-3-hydroxypropan-2-yl acetate (Iodixanol Impurity) (CAS 2730989-02-1)
- (3AR,3'aS,3''aR,3'''aR,3''''aR,8aR,8'aS,8''aR,8'''aR,8''''aR)-1,1',1'',1''',1''''-pentamethyl-2,2',2'',2''',2'''',3,3',3'',3''',3'''',8,8a,8',8'a,8'',8''a,8''',8'''a,8'''',8''''a-icosahydro-1H,1'H,1''H,1'''H,1''''H-3a,7':3'a,3''a:7'',3'''a:7''',3''''a-quinquepyrrolo[2,3-b]indole (CAS 52617-25-1)
- tert-butyl (4-((3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)propyl)(tert-butoxycarbonyl)amino)butyl)(3-palmitamidopropyl)carbamate (CAS 1263046-88-3)
- Fmoc-Phe-Lys(Trt)-PAB (CAS 1116085-98-3)
- Radezolid impurity 1 (CAS 138829-43-3)
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- 3-Chloro-2-(2,4-dichlorophenoxy)-5-(trifluoromethyl)pyridine (CAS 1053656-99-7)
- (1R,2S)-2-(4-bromophenyl)cyclopropane-1-carboxylic acid (CAS 2137065-16-6)
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- 3,5-Dimethyl-N-(thiophen-3-ylmethyl)-1H-pyrazole-4-sulfonamide (CAS 1286695-57-5)
- Cefmetazole Impurity 13 (CAS CATO-C4X-150713)
- 4-Ethoxy-2,6,7-trimethyl-1,2,3,4-tetrahydroquinoline (CAS 503438-75-3)
- Semaglutide Impurity 165 (CAS CATO-C4X-2226165)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com