Duloxetine Impurity 58 CAS 2735518-05-3
| CAS No. | 2735518-05-3 |
| Molecular Formula | C8H11NOS |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 205.70 g/mol gives Duloxetine Impurity 58 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Duloxetine Impurity 58 (CAS 2735518-05-3, C8H11NOSHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C8H11NOSHCl, Duloxetine Impurity 58 contains an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 205.70 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Duloxetine Impurity 58 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H11NOS HCl |
| Molecular Weight | 205.70 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Duloxetine Standards
- Duloxetine EP Impurity E HCl (CAS 1033719-36-6)
- Duloxetine EP Impurity E (CAS 1033803-59-6)
- Duloxetine Impurity 55 (CAS 1045348-04-6)
- Duloxetine Impurity 9 (CAS 110-14-5)
- rac-Duloxetine EP Impurity F HCl (CAS 1104890-90-5)
- Duloxetine EP Impurity B (CAS 116539-55-0)
- Duloxetine Impurity (CAS 116539-57-2)
- Duloxetine (CAS 116539-59-4)
Recommended Standards
- Ropivacaine EP Impurity D (CAS 98626-59-6)
- Clindamycin Impurity 96 (CAS CATO-C4X-134196)
- Montelukast Impurity 24 (CAS CATO-C4X-103124)
- 2-(3-(3-Bromophenyl)propanoyl)benzonitrile (CAS 898782-09-7)
- Rel-((1r,1's,4R,4'R)-4'-butyl-[1,1'-bi(cyclohexan)]-4-yl)methanol (CAS 88416-94-8)
- Naftopidil Impurity 1 (CAS 2461-42-9)
- (1-Cyclopropyl-3-pyrrolidinyl)methanol (CAS 1017476-51-5)
- 2′-Deoxy-β-L-uridine (CAS 31501-19-6)
- H-Gly-Trp-OH (CAS 2390-74-1)
- Cholecystokinin Octapeptide (1-3) (desulfated) H-Asp-Tyr-Met-OH (CAS 121880-94-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com