Calcitonin Impurity 12 CAS CATO-C4X-221812

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-221812
Molecular FormulaC145H239N43O49S2
Molecular Weight3432.84 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Calcitonin Impurity 12 CAS CATO-C4X-221812 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 3432.84 g/mol gives Calcitonin Impurity 12 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

As a process- or degradation-related impurity, Calcitonin Impurity 12 (CAS CATO-C4X-221812, C145H239N43O49S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Structurally, Calcitonin Impurity 12 (C145H239N43O49S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 48.0, corresponding to approximately 48 ring(s) or double-bond equivalent(s). With a molecular weight of 3432.84 g/mol, it falls into the high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC145H239N43O49S2
Molecular Weight3432.84 g/mol
Purity>95%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)48.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms43
Sulfur Atoms2

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