(3,5-Bis(trifluoromethyl)phenyl)bis(3-nitrophenyl)phosphineoxide CAS 299176-63-9
| CAS No. | 299176-63-9 |
| Molecular Formula | C20H11F6N2O5P |
| Molecular Weight | 504.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures (3,5-Bis(trifluoromethyl)phenyl)bis(3-nitrophenyl)phosphineoxide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies (3,5-Bis(trifluoromethyl)phenyl)bis(3-nitrophenyl)phosphineoxide (CAS 299176-63-9), a certified reference material (molecular formula C20H11F6N2O5P, MW 504.28 g/mol) for analytical method development and quality control.
The molecular framework of (3,5-Bis(trifluoromethyl)phenyl)bis(3-nitrophenyl)phosphineoxide (C20H11F6N2O5P) is characterized by a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C20H11F6N2O5P |
| Molecular Weight | 504.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Bis Standards
- 4,4-Bis(trifluoromethyl)-2-iodo-5,5,6,6,7,7,7-heptafluoroheptan-1-ol (CAS 1350637-03-4)
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- 3-((3,5-Bis(trifluoromethyl)benzyl)amino)-4-(((1S,2S)-2-(piperidin-1-yl)cyclohexyl)amino)cyclobut-3-ene-1,2-dione (CAS 1570357-03-7)
- 5-({[3,5-bis(trifluoromethyl)phenyl]methyl}sulfanyl)-8,9-dimethoxy-2H,3H-imidazo[1,2-c]quinazolin-2-one (CAS 439109-35-0)
- (3,5-Bis(trifluoromethyl)phenyl)tributylstannane (CAS 717918-62-2)
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Recommended Standards
- Iopamidol Impurity 30 (CAS 2756222-41-8)
- 5-(3-Nitrophenyl)furan-2-carboxylicacid[2-(4-bromophenyl)benzooxazol-5-yl]amide (CAS 309292-41-9)
- Iopamidol Impurity 29 (CAS 2756222-40-7)
- Thiamine Triphosphate (CAS 3475-65-8)
- 3-chloro-1-(4-fluorophenyl)propan-1-ol (CAS 31736-75-1)
- N-(2-((6-(4-Fluorophenyl)pyridazin-3-yl)oxy)ethyl)benzenesulfonamide (CAS 920256-31-1)
- 5-(Methoxycarbonyl)pyridine-3-boronic acid, 97% (CAS 871329-53-2)
- Methyl 4-(4-piperidinylmethoxy)benzoatehydrochloride (CAS 1219963-77-5)
- Tofacitinib Impurity 249 (CAS CATO-C4X-1079249)
- 1-(2-(Cyclopentylmethoxy)ethyl)-1h-pyrazol-4-amine (CAS 1539453-44-5)
- 1-(4-Nitrophenyl)-3-(oxolan-2-ylmethyl)urea (CAS 903708-97-4)
- 6-Butyl-2-(2-hydroxy-3-(2-phenylpropan-2-yl)-5-(2,4,4-trimethylpentan-2-yl)phenyl)-[1,2,3]triazolo[4,5-f]isoindole-5,7(2H,6H)-dione (CAS 945857-19-2)
- 3-(4-Bromo-2,5-difluoro-phenyl)oxetan-3-ol (CAS 2065235-77-8)
- His-Cyclic-Semaglutide (CAS CATO-C4X-2226182)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com