Beclomethasone dipropionate Impurity 23 CAS CATO-C4X-147423
| CAS No. | CATO-C4X-147423 |
| Molecular Formula | C22H29ClO6 |
| Molecular Weight | 424.92 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Beclomethasone dipropionate Impurity 23 (C22H29ClO6) contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Beclomethasone dipropionate Impurity 23 (CAS CATO-C4X-147423) is a certified pharmaceutical impurity reference standard with the molecular formula C22H29ClO6 and a molecular weight of 424.92 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H29ClO6 |
| Molecular Weight | 424.92 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Beclomethasone Standards
- Beclomethasone dipropionate Impurity 41 (CAS CATO-C4X-147441)
- Beclomethasone dipropionate Impurity 40 (CAS CATO-C4X-147440)
- Beclomethasone-d5 (CAS 1263143-48-1)
- Beclomethasone (CAS CATO-C4X-147422)
- Beclomethasone (CAS 4419-39-0)
- Beclomethasone-Δ17,20 21-Aldehyde(E/Z Mixture) (CAS 1174035-77-8&1174035-80-3)
- Beclomethasone-17-Monopropionate-d3 (CAS CATO-C4X-147426)
- Beclomethasone 17-Propionate-d5 (CAS CATO-C4X-147425)
Recommended Standards
- Loratadine Impurity 65 (CAS CATO-C4X-142665)
- Beclometasone Impurity 28 (CAS CATO-C4X-147428)
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- Leflunomide Impurity 2 (CAS 827029-20-9)
- Tetrabenazine Impurity 67 (CAS CATO-C4X-274867)
- Roflumilast Impurity 53 (CAS 2204417-23-0)
- 5-Fluoro-4-hydrazinylpyrimidin-2(1H)-one (CAS 339363-33-6)
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- 5-(Thiophen-3-ylmethyl)-1,3,4-oxadiazole-2-thiol (CAS 262856-02-0)
- Ranitidine N,S-Dioxide (CAS 1185237-42-6)
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- Tert-butyl 1-amino-2-methylcyclohexane-1-carboxylate (CAS 1247095-41-5)
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