Oseltamivir impurity 266 CAS 2762080-42-0
| CAS No. | 2762080-42-0 |
| Molecular Formula | C14H23ClO4 |
| Molecular Weight | 290.78 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Oseltamivir impurity 266 (CAS 2762080-42-0, C14H23ClO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Oseltamivir impurity 266 (C14H23ClO4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 290.78 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H23ClO4 |
| Molecular Weight | 290.78 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | Cl-containing |
Related Oseltamivir Standards
- Oseltamivir Impurity 124 (CAS CATO-C4X-1720124)
- Oseltamivir Impurity 90 (CAS CATO-C4X-172090)
- Oseltamivir Impurity 93 (CAS CATO-C4X-172093)
- Oseltamivir Acid-13CD3 (CAS 187227-45-8 (unlabeled))
- Oseltamivir EP Impurity C-d3 (CAS CATO-C4X-1720233)
- Oseltamivir-d3 Acid (CAS 1242184-43-5)
- Oseltamivir impurity N1 (CAS 1268086-96-9)
- Oseltamivir Impurity 138 (CAS CATO-C4X-1720138)
Recommended Standards
- 3-(4-Chlorophenyl)adamantane-1-carboxylic acid (CAS 56531-62-5)
- Clemastine Impurity 37 (CAS CATO-C4X-183737)
- 9b-(4-Chlorophenyl)-2,3,5,9b-tetrahydro-1H-imidazo[2,1-a]isoindol-5-ol-d4 (CAS 1346601-86-2)
- 2-((2-aminobenzyl)(methyl)amino)-1-(4-chlorophenyl)ethanol (CAS 102436-79-3)
- Alprazolam EP Impurity A (CAS 27537-87-7)
- Doripenem Impurity 1 (CAS CATO-C4X-16211)
- Sildenafil Impurity N6 (CAS 1004455-71-3)
- Fluorouracil Impurity 31 (CAS 58629-87-1)
- 2-(Dimethylamino)-4,6-dimethylnicotinonitrile (CAS 1233123-61-9)
- Tris(4-tert-butyl-3-hydroxy-2,6-dimethylbenzyl) isocyanurate (CAS 40601-76-1)
- (2-Fluoro-6-methoxy-3-methylphenyl)boronic acid (CAS 1451392-12-3)
- Ethyl 2-(4-Fluorobenzyl)oxazole-4-carboxylate (CAS 500367-20-4)
- N-((5-(Dimethylamino)naphthalen-1-yl)sulfonyl)-N-methylglycine (CAS 1093-96-5)
- Semaglutide impurity 107 (CAS CATO-C4X-2226107)
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