2,6-Difluoro-4-(trifluoromethyl)phenol CAS 276244-25-8
| CAS No. | 276244-25-8 |
| Molecular Formula | C7H3F5O |
| Molecular Weight | 198.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 198.09 g/mol gives 2,6-Difluoro-4-(trifluoromethyl)phenol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2,6-Difluoro-4-(trifluoromethyl)phenol (CAS 276244-25-8), molecular formula C7H3F5O and molecular weight 198.09 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 2,6-Difluoro-4-(trifluoromethyl)phenol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 198.09 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H3F5O |
| Molecular Weight | 198.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Difluoro Standards
- 3,5-Difluoro-4-(trifluoromethyl)phenol (CAS 116640-11-0)
- 2,3-Difluoro-4-(trifluoromethyl)phenol (CAS 116640-12-1)
- 1,2-Difluoro-4-(trifluoromethoxy)benzene (CAS 1378671-81-8)
- 1,3-Difluoro-5-(trifluoromethoxy)benzene (CAS 1404194-50-8)
- 2,4-Difluoro-1-(trifluoromethoxy)benzene (CAS 1404194-72-4)
- 1,4-Difluoro-2-(trifluoromethoxy)benzene (CAS 1404195-06-7)
- 1,3-Difluoro-2-(trifluoromethoxy)benzene (CAS 153338-23-9)
- 1,2-Difluoro-3-(trifluoromethoxy)benzene (CAS 158178-35-9)
Recommended Standards
- 2,6-Difluoro-3-(trifluoromethyl)phenol (CAS 2149589-77-3)
- 3,5-Difluoro-4-(trifluoromethyl)pyridin-2-amine (CAS 883498-68-8)
- 2,3,4,5,6-Pentafluoroanisole (CAS 389-40-2)
- 5-(Difluoromethoxy)-1,2,3-trifluoro-benzene (CAS 478303-15-0)
- 5-(4-Bromophenyl)-2-methyl-2H-tetrazole (CAS 69746-36-7)
- 1-(2,6-Dimethylpyrimidin-4-yl)pyrrolidin-3-ol (CAS 1338656-96-4)
- Cilazapril Monohydrate (CAS 92077-78-6)
- 3-(Methylamino)butanoic acid (CAS 167222-94-8)
- (4-(Furan-2-yl)phenyl)methanamine (CAS 771573-27-4)
- (6-Aminopyrimidin-4-yl)-N-(tert-butoxycarbonyl)carbamic acid tert-butyl ester (CAS 1364663-35-3)
- Dimethyl 5-(4-chlorophenyl)-1h-pyrazole-1,3-dicarboxylate (CAS 1017499-24-9)
- 8-(Chlorosulfonyl)-3,4-dihydro-2H-benzo[b][1,4]dioxepine-6-carboxylic acid (CAS 66410-81-9)
- tert-Butyl 2',4'-dihydro-1'H-spiro[morpholine-2,3'-quinoline]-4-carboxylate (CAS 1160247-84-6)
- C-telopeptide (CAS 162929-64-8)
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