1,2-Difluoro-3-(trifluoromethoxy)benzene CAS 158178-35-9
| CAS No. | 158178-35-9 |
| Molecular Formula | C7H3F5O |
| Molecular Weight | 198.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 198.09 g/mol gives 1,2-Difluoro-3-(trifluoromethoxy)benzene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1,2-Difluoro-3-(trifluoromethoxy)benzene (CAS 158178-35-9) is a high-purity analytical reference standard with the molecular formula C7H3F5O and a molecular weight of 198.09 g/mol.
1,2-Difluoro-3-(trifluoromethoxy)benzene (C7H3F5O) contains a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1,2-Difluoro-3-(trifluoromethoxy)benzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H3F5O |
| Molecular Weight | 198.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F-containing |
Related Difluoro Standards
- 3,5-Difluoro-4-(trifluoromethyl)phenol (CAS 116640-11-0)
- 2,3-Difluoro-4-(trifluoromethyl)phenol (CAS 116640-12-1)
- 1,2-Difluoro-4-(trifluoromethoxy)benzene (CAS 1378671-81-8)
- 1,3-Difluoro-5-(trifluoromethoxy)benzene (CAS 1404194-50-8)
- 2,4-Difluoro-1-(trifluoromethoxy)benzene (CAS 1404194-72-4)
- 1,4-Difluoro-2-(trifluoromethoxy)benzene (CAS 1404195-06-7)
- 1,3-Difluoro-2-(trifluoromethoxy)benzene (CAS 153338-23-9)
- 2,4-Difluoro-5-(trifluoromethyl)phenol (CAS 1632283-20-5)
Recommended Standards
- 2,3-Difluoro-5-(trifluoromethyl)phenol (CAS 164790-01-6)
- 3,6-dichloro-N,N-dimethyl-pyridazin-4-amine (CAS 17258-35-4)
- 2,3,4,5,6-Pentafluoroanisole (CAS 389-40-2)
- 2,6-Difluoro-3-(trifluoromethyl)phenol (CAS 2149589-77-3)
- (S)-N-(1-(4-Methylquinazolin-2-yl)-2-phenylethyl)formamide (CAS 923603-71-8)
- {2-[3-(6-Dimethylamino-4-trifluoromethyl-pyridin-2-yl)-phenoxy]-propionylamino}-acetic acid ethyl ester (CAS 1311279-83-0)
- 4-(Aminomethyl)-1-(methylthio)hexan-3-ol (CAS 1506332-37-1)
- Salbutamol Impurity 208 (CAS CATO-C4X-1176208)
- Mometasone Impurity 51 (CAS CATO-C4X-170451)
- 2H-Pyran-2,4(3H)-dione (CAS 31470-16-3)
- Lifitegrast Impurity 131 (CAS CATO-C4X-2409131)
- Ethyl 6-oxo-5,6-dihydropyrazine-2-carboxylate (CAS 1286744-23-7)
- (1R,2R)-1,2-Cyclopentanediamine dihydrochloride (CAS 1030390-38-5)
- Antistasin-Related Peptide (CAS 161561-46-2)
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