Bupropion Impurity 03 CAS 2763780-10-3
| CAS No. | 2763780-10-3 |
| Molecular Formula | C13H17ClN2O2 |
| Molecular Weight | 268.74 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Bupropion Impurity 03 (C13H17ClN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 268.74 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a process- or degradation-related impurity, Bupropion Impurity 03 (CAS 2763780-10-3, C13H17ClN2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Bupropion Impurity 03 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H17ClN2O2 |
| Molecular Weight | 268.74 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Bupropion Standards
- Bupropion impurity 60 (CAS 1193779-48-4)
- Bupropion Impurity 7 (CAS 92264-81-8)
- Bupropion Impurity 9 (CAS 103175-61-7)
- Bupropion Impurity 20 (CAS 1261791-08-5)
- Bupropion Impurity 15 (CAS 92821-91-5)
- Bupropion Impurity 4 (CAS 1246812-57-6)
- Bupropion Impurity 21 (CAS 2133460-42-9)
- Bupropion Impurity 22 (CAS 2133460-43-0)
Recommended Standards
- 8-(4-Chlorophenyl)-8-oxooctanoic acid (CAS 35333-22-3)
- Butyl 4-(4-chlorophenyl)-4-oxobutanoate (CAS 340283-98-9)
- 8-(3-Chlorophenyl)-8-oxooctanoic acid (CAS 898765-75-8)
- Clomifenecitrate (CAS 88431-47-4)
- Topiramate Impurity 35 (CAS CATO-C4X-176835)
- Cimetidine Impurity 12 (CAS 75850-09-8)
- Ketoprofen Impurity 79 (CAS 61467-02-5)
- 1-(Octahydro-pyrrolo[3,4-b]azepin-7-yl)-ethanone (CAS 1316220-00-4)
- 2-Methyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine (CAS 1159882-42-4)
- N,N-Diethylbenzenesulfonamide (CAS 1709-50-8)
- 1-(Bromomethyl)-3-methyl-1-(2-propoxyethoxy)cyclohexane (CAS 1341551-29-8)
- 5-Methanesulfonyl-2-methoxyaniline (CAS 20945-70-4)
- 1236266-39-9 2-Amino-1-(4-benzyl-1-piperazinyl)-3-phenyl-1-propanone hydrochloride 2916AD C20H26ClN3O (CAS 1236266-39-9)
- Brain Injury Derived Neurotrophic Peptide (H-3914.0001) (CAS 148330-12-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com