Flunarizine EP Impurity A CAS 27649-60-9
| CAS No. | 27649-60-9 |
| Molecular Formula | C17H18F2N2 |
| Molecular Weight | 288.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Flunarizine EP Impurity A.
Flunarizine EP Impurity A (CAS 27649-60-9) is a high-purity analytical reference standard with the molecular formula C17H18F2N2 and a molecular weight of 288.34 g/mol.
Flunarizine EP Impurity A (C17H18F2N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Flunarizine EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H18F2N2 |
| Molecular Weight | 288.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Flunarizine Standards
- Flunarizine EP Impurity A (CAS 27469-60-9)
- Flunarizine Impurity 21 (CAS 39918-90-6)
- Flunarizine impurity 49 (CAS 2922257-65-4)
- Flunarizine Impurity 16 (CAS 345-90-4)
- Flunarizine Impurity 22 (CAS CATO-C4X-135722)
- Flunarizine Impurity 15 (CAS 365-20-8)
- Flunarizine Impurity 32 (CAS 141528-78-1)
- Flunarizine Impurity 12 (CAS 88172-16-1)
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