Flunarizine Impurity 12 CAS 88172-16-1
| CAS No. | 88172-16-1 |
| Molecular Formula | C22H26N2 |
| Molecular Weight | 318.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Flunarizine Impurity 12 (CAS 88172-16-1, C22H26N2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Flunarizine Impurity 12 (C22H26N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 318.46 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H26N2 |
| Molecular Weight | 318.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Nitrogen Atoms | 2 |
Related Flunarizine Standards
- Flunarizine Impurity 32 (CAS 141528-78-1)
- Flunarizine impurity 49 (CAS 2922257-65-4)
- Flunarizine Impurity 21 (CAS 39918-90-6)
- Flunarizine EP Impurity A (CAS 27649-60-9)
- Flunarizine EP Impurity A (CAS 27469-60-9)
- Flunarizine Impurity 16 (CAS 345-90-4)
- Flunarizine Impurity 22 (CAS CATO-C4X-135722)
- Flunarizine Impurity 15 (CAS 365-20-8)
Recommended Standards
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