5-Chloro-2-methyl-7H-[1,2]oxazolo[2,3-a]pyrimidin-7-one CAS 278614-92-9
| CAS No. | 278614-92-9 |
| Molecular Formula | C7H5ClN2O2 |
| Molecular Weight | 184.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Chloro-2-methyl-7H-[1,2]oxazolo[2,3-a]pyrimidin-7-one is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-Chloro-2-methyl-7H-[1,2]oxazolo[2,3-a]pyrimidin-7-one (CAS 278614-92-9), a certified reference material (molecular formula C7H5ClN2O2, MW 184.58 g/mol) for analytical method development and quality control.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 5-Chloro-2-methyl-7H-[1,2]oxazolo[2,3-a]pyrimidin-7-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 184.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Chloro-2-methyl-7H-[1,2]oxazolo[2,3-a]pyrimidin-7-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5ClN2O2 |
| Molecular Weight | 184.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 7-Chloro-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one (CAS 105544-33-0)
- 4-Chloro-6-methoxy-1H-pyrazolo[3,4-d]pyrimidine (CAS 1060816-54-7)
- (6-Chloro-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methanol (CAS 1175301-94-6)
- 4-Chloro-3,7-dihydro-1H-pyrrolo[2,3-b]pyridine-2,6-dione (CAS 1190313-44-0)
- 6-Chloro-4-hydroxy-1H-pyrrolo[2,3-b]pyridin-2(3H)-one (CAS 1190314-80-7)
- 5-Chloro-1H-pyrrolo[2,3-b]pyridine-2,6(3H,7H)-dione (CAS 1190315-19-5)
- 8-CHLORO-1H-PYRIDO[2,3-B][1,4]OXAZIN-2(3H)-ONE (CAS 1198154-62-9)
- 2-Chloro-5-formylbenzoic acid (CAS 1206625-81-1)
Recommended Standards
- 5-Chloro-2-hydroxyisophthalaldehyde (CAS 32596-43-3)
- 5-Chloro-3-hydroxyisobenzofuran-1(3H)-one (CAS 70097-46-0)
- 5-Chloro-2-formylbenzoic Acid (CAS 4506-45-0)
- 5-Chloro-7-methoxy-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 89581-76-0)
- 1,1'-(Hexane-1,6-diyl)bis(3-benzylurea) (CAS 39072-70-3)
- (2-Amino-4-bromophenyl)(4-(methylsulfonyl)piperazin-1-yl)methanone (CAS 1539817-33-8)
- (3-(4-(Tert-butoxycarbonyl)piperazin-1-yl)-4,5-difluorophenyl)boronic acid (CAS 1704067-25-3)
- Ethyl 2-(chloromethyl)-4-methylquinoline-3-carboxylate (CAS 790263-88-6)
- 4-Bromo-5-Nitro-1H-Indole (CAS 1934562-99-8)
- 4-(3-(4-Chlorophenyl)-1H-1,2,4-triazol-5-yl)-2-methoxyphenol (CAS 1416347-55-1)
- 2-Nitro-3-(2,2,2-trifluoroethoxy)pyridine (CAS 1532517-67-1)
- 7A-methyltetrahydropyrrolo[1,2-c]oxazole-1,3-dione (CAS 63427-92-9)
- 5-Methyl-2,3-dihydrobenzofuran-4-ol (CAS 600176-61-2)
- Tripeptide-10 citrulline (CAS 960531-53-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com