Methyldopa EP Impurity D CAS 2799-15-7
| CAS No. | 2799-15-7 |
| Molecular Formula | C10H13NO4 |
| Molecular Weight | 211.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Methyldopa EP Impurity D (C10H13NO4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Methyldopa EP Impurity D (CAS 2799-15-7), a pharmacopoeial impurity reference standard (molecular formula C10H13NO4, MW 211.21 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H13NO4 |
| Molecular Weight | 211.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Methyldopa Standards
- DL-Methyldopa (CAS 55-40-3)
- Methyldopa Impurity 15 (CAS CATO-C4X-169315)
- Methyldopa EP Impurity B (Racemate) (CAS 7383-30-4)
- Methyldopa EP Impurity A (CAS 6739-31-7)
- Methyldopa Impurity 14 (CAS CATO-C4X-169314)
- Methyldopa Impurity 13 (CAS 94782-89-5)
- Methyldopa EP Impurity C (CAS 39948-18-0)
- Methyldopa O-Sulfate (Meta) (CAS 72572-96-4)
Recommended Standards
- Methyl 6-(hydroxymethyl)-2-methoxy-5-methylnicotinate (CAS 2750929-30-5)
- N-(2,5-dimethylfuran-3-carbonyl)-N-methylglycine (CAS 954259-21-3)
- Methyl 6-(2-methoxyethoxy)nicotinate (CAS 2379322-08-2)
- N-Hydroxy-3,4-dimethoxy-N-methylbenzamide (CAS 82461-57-2)
- Vonoprazan Impurity 222 HCl (CAS 2231094-87-2 (free base))
- Landiolol Impurity 71 (CAS CATO-C4X-262171)
- Sulfasalazine impurity 15 (CAS CATO-C4X-141915)
- 1-(2-(4-Chlorophenyl)quinolin-4-yl)-N-ethylpiperidine-4-carboxamide (CAS 103914-11-0)
- 1-(4-Bromophenyl)-2-(pyridin-2-yl)ethan-1-amine (CAS 1039865-46-7)
- (3-Oxo-1,3-dihydro-2-benzofuran-1-yl)urea (CAS 4741-69-9)
- Isothiazole-4,5-dicarboxylic acid (CAS 66882-70-0)
- 1-(5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}thiophen-2-yl)ethan-1-one (CAS 321432-63-7)
- 5-(5-Methoxy-2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)pyridin-2-amine (CAS 951238-13-4)
- Cholecystokinin Octapeptide (1-4) (desulfated) (CAS 80790-40-5)
Why CATO?
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