Biotin Impurity 03 CAS 28092-62-8
| CAS No. | 28092-62-8 |
| Molecular Formula | C19H18N2O3 |
| Molecular Weight | 322.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Biotin Impurity 03 (C19H18N2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Biotin Impurity 03 (CAS 28092-62-8, C19H18N2O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Biotin Impurity 03 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H18N2O3 |
| Molecular Weight | 322.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Nitrogen Atoms | 2 |
Related Biotin Standards
Recommended Standards
- Benzyl tert-butyl (2-oxopropane-1,3-diyl)dicarbamate (CAS 877317-26-5)
- Dimethylphenyl Actyl Biotin (CAS 40222-71-7)
- Benzyl 2-oxospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate (CAS 908287-35-4)
- Diphenyl((propylsulfonyl)methyl)phosphine oxide (CAS 93017-17-5)
- Propafenone EP Impurity H(R-isomer) (CAS 27439-12-9)
- Edoxaban Impurity N46 (CAS 1353893-25-0)
- Tamsulosin Impurity 28 (CAS 1495375-67-1)
- 2-(Chloromethyl)-6-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 87591-74-0)
- N-(4-Fluoro-2-methoxy-5-nitrophenyl)formamide (CAS 1899924-29-8)
- 3-[(2-fluorophenyl)sulfanyl]propanamide (CAS 1097789-62-2)
- 2-((4-Methoxy-N-phenylphenyl)sulfonamido)-N,N-dimethylacetamide (CAS 339013-34-2)
- 2-(4-tert-Butylphenoxy)-4-(dimethylamino)pyridine-3-carbonitrile (CAS 341967-06-4)
- 1-[4-(Trifluoromethyl)benzyl]piperidin-4-amine (CAS 149401-02-5)
- Tirzepatide Impurity 14 (CAS CATO-C4X-324014)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com