Biotin impurity 22 CAS 87585-00-0
| CAS No. | 87585-00-0 |
| Molecular Formula | C19H18N2O3 |
| Molecular Weight | 322.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Biotin impurity 22 (CAS 87585-00-0), a pharmacopoeial impurity reference standard (molecular formula C19H18N2O3, MW 322.36 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Biotin impurity 22 (C19H18N2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 322.36 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Biotin impurity 22 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H18N2O3 |
| Molecular Weight | 322.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Nitrogen Atoms | 2 |
Related Biotin Standards
Recommended Standards
- Eltrombopag Impurity 14 (CAS CATO-C4X-119814)
- N-nitroso-alcaftadine (CAS CATO-C4X-17955)
- Tamsulosin Impurity 47 (CAS CATO-C4X-118747)
- Neomycin Sulfate EP Impurity A (CAS 3947-65-7)
- Tunodafil Impurity 5 (CAS CATO-C4X-31105)
- Rosuvastatin Impurity 76 (CAS CATO-C4X-116976)
- Oseltamivir Impurity 27 (CAS CATO-C4X-1720227)
- tert-Butylamine Hydrobromide (CAS 60469-70-7)
- (2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(3-((E)-2-cyanovinyl)-9H-carbazol-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite (CAS 1157899-72-3)
- Candesartan Cilexetil EP Impurity B (CAS 869631-11-8)
- 2-(2-Amino-6-(difluoromethyl)-4-fluoropyridin-3-yl)acetic acid (CAS 1805942-60-2)
- Razaxaban - API Standards (CAS 218298-21-6)
- 2-fluoro-2-methylhexanoic acid (CAS 74106-60-8)
- Tirzepatide Impurity 22 X TFA Salt (CAS CATO-C4X-324022)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com