Chlorpheniramine Impurity 15 CAS 120244-82-8
| CAS No. | 120244-82-8 |
| Molecular Formula | C16H19ClN2O |
| Molecular Weight | 290.79 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Chlorpheniramine Impurity 15 (CAS 120244-82-8), a pharmacopoeial impurity reference standard (molecular formula C16H19ClN2O, MW 290.79 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C16H19ClN2O, Chlorpheniramine Impurity 15 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 290.79 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C16H19ClN2O |
| Molecular Weight | 290.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorpheniramine Standards
- R-Chlorpheniramine N-Oxide (CAS 142494-45-9)
- S-Chlorpheniramine N-0xide (CAS 142494-46-0)
- Chlorpheniramine Impurity 14 (CAS CATO-C4X-118814)
- Chlorpheniramine-d6 (CAS 1185054-60-7)
- Chlorpheniramine Nitrile-d6 (CAS 1329488-38-1)
- Chlorpheniramine Impurity 19 (CAS CATO-C4X-118819)
- Chlorpheniramine Impurity 36 (CAS CATO-C4X-118836)
- Chlorpheniramine Impurity 38 (CAS CATO-C4X-118838)
Recommended Standards
- Mirabegron impurity 122 (CAS 391901-43-2)
- Chlorphenamine impurity 54 (CAS CATO-C4X-118854)
- Tert-butyl 3-[(2-chloroacetamido)methyl]piperidine-1-carboxylate (CAS 642443-45-6)
- tert-Butyl ((1r,4r)-4-(2-chloroacetamido)cyclohexyl)carbamate (CAS 873537-67-8)
- Flurbiprofen Impurity 80 (CAS CATO-C4X-144480)
- Rivastigmine Impurity 15 (CAS 71607-31-3(free base))
- Tretinoin EP Impurity G (CAS 13100-69-1)
- 2-Amino-4,6-dibromobenzaldehyde (CAS 135690-29-8)
- 2-([1,1'-Biphenyl]-2-yloxy)ethyl acrylate (CAS 91442-24-9)
- 5-(2,2-Difluoroethenyl)-1-[(2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]Pyrimidine-2,4-Dione (CAS 108711-80-4)
- (2,4-Di-tert-butyl-6-methoxyphenyl)boronic acid (CAS 175602-46-7)
- 2-(4-(Aminomethyl)-5-cyano-6-(difluoromethyl)pyridin-3-yl)acetic acid (CAS 1804420-55-0)
- Oleoyl chloride (CAS 112-77-6)
- Semaglutide impurity 269 (CAS CATO-C4X-2226269)
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