N,N-Diethyl-6-methyl-5-nitro-2-pyridinamine CAS 28489-43-2
| CAS No. | 28489-43-2 |
| Molecular Formula | C10H15N3O2 |
| Molecular Weight | 209.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N,N-Diethyl-6-methyl-5-nitro-2-pyridinamine.
N,N-Diethyl-6-methyl-5-nitro-2-pyridinamine (CAS 28489-43-2), molecular formula C10H15N3O2 and molecular weight 209.25 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, N,N-Diethyl-6-methyl-5-nitro-2-pyridinamine (C10H15N3O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 209.25 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H15N3O2 |
| Molecular Weight | 209.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Nitrogen Atoms | 3 |
Recommended Standards
- N,N,3-Trimethyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-6-carboxamide (CAS 2137463-30-8)
- N-Butyl-N-(6-oxo-1,6-dihydropyridazin-3-yl)acetamide (CAS 88259-88-5)
- N-(sec-Butyl)-N-(6-oxo-1,6-dihydropyridazin-3-yl)acetamide (CAS 88259-89-6)
- N-isopentyl-3-nitropyridin-2-amine (CAS 931950-35-5)
- 5-Bromo-2-isobutoxy-N-methylnicotinamide (CAS 1774899-32-9)
- 4-(4-Nitrobenzylidene)-2-phenyloxazol-5(4H)-one (CAS 7152-75-2)
- Ethyl 2-[4-(2,6-dimethylphenyl)piperazin-1-yl]-5-(4-methylphenyl)-1H-pyrrole-3-carboxylate (CAS 338406-22-7)
- 1,4-Diazabicyclo[2.2.2]Octane-2-carbonitrile (CAS 1394774-46-9)
- 1-(1,3-dimethylbutyl)piperazine dihydrochloride 1171587-00-0 (CAS 1171587-00-0)
- 2-(1H-1,2,4-triazol-1-ylmethyl)morpholine hydrochloride (CAS 1315366-86-9)
- 2-{[(3,4-dichlorophenyl)methyl]sulfanyl}-5-methoxy-N-(propan-2-yl)pyrimidin-4-amine (CAS 338954-53-3)
- 2-[4-(Pyrrolidin-1-yl)piperidin-1-yl]ethan-1-amine (CAS 1067659-34-0)
- 2-(4-Oxo-7-(trifluoromethyl)quinolin-1(4H)-yl)acetonitrile (CAS 1133123-06-4)
- Semaglutide impurity 57 (CAS 2773558-06-6)
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