Ethyl 5-(2-chloroacetamido)-3-methylthiophene-2-carboxylate CAS 285138-55-8
| CAS No. | 285138-55-8 |
| Molecular Formula | C10H12ClNO3S |
| Molecular Weight | 261.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 5-(2-chloroacetamido)-3-methylthiophene-2-carboxylate.
Ethyl 5-(2-chloroacetamido)-3-methylthiophene-2-carboxylate (CAS 285138-55-8) is a high-purity analytical reference standard with the molecular formula C10H12ClNO3S and a molecular weight of 261.73 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, Ethyl 5-(2-chloroacetamido)-3-methylthiophene-2-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 261.73 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Ethyl 5-(2-chloroacetamido)-3-methylthiophene-2-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H12ClNO3S |
| Molecular Weight | 261.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Ethyl Standards
- 2-(2-Chloroacetamido)-N,N,4-trimethylthiazole-5-carboxamide (CAS 545437-13-6)
- Ethyl 2-(2-chloroacetamido)-5-methylthiophene-3-carboxylate (CAS 669747-36-8)
- Methyl 2-(2-chloroacetamido)-4,5-dimethylthiophene-3-carboxylate (CAS 448199-06-2)
- Methyl 2-(2-chloroacetamido)-3-cyclohexylpropanoate (CAS 318949-36-9)
- Ethyl 2-(2-chloroacetamido)-4-thiazoleacetate (CAS 19749-93-0)
- Ethyl 2-(2-chloroacetamido)-4-methylthiazole-5-carboxylate (CAS 6125-37-7)
- 2-(2-Chloroacetamido)-4-ethyl-5-methylthiophene-3-carboxamide (CAS 544657-74-1)
- 3-(2-Chloroacetamido)naphthalene-2-carboxylic acid (CAS 1181868-84-7)
Recommended Standards
- Glipizide Impurity 6 (CAS 35450-53-4)
- ethyl (2E)-4-chloro-3-hydroxy-2-(4-methyl-1,3-thiazol-2-yl)but-2-enoate (CAS 848658-80-0)
- Di(furan-2-yl)tellane (CAS 89019-01-2)
- Methyl 2-[(chloroacetyl)amino]-5-ethylthiophene-3-carboxylate (CAS 515832-73-2)
- 5-(Pyridin-2-yl)furan-2-carboxylic acid (CAS 862089-25-6)
- 5-Sulfamoylthiophene-2-carboxylic acid (CAS 7353-87-9)
- 2-Bromo-6-methyl-4-(trifluoromethyl)aniline (CAS 1100212-65-4)
- 2-Chloro-6-cyanopyridine-4-sulfonyl chloride (CAS 1393550-71-4)
- 2-([2-(4-Fluorophenyl)ethyl]amino)acetonitrile (CAS 864960-91-8)
- 3-Amino-3-(5-(hydroxymethyl)furan-2-yl)propanoic acid (CAS 682803-04-9)
- 5-(4-Chlorophenyl)-N-((2-(2,2,2-trifluoroethoxy)pyridin-3-yl)methyl)nicotinamide (CAS 1026822-49-0)
- Atogepant Impurity 3 (CAS 1455358-11-8)
- Atorvastatin Impurity 17 (CAS 1795791-15-9)
- Semaglutide impurity 56 (CAS CATO-C4X-222656)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com