Methyl 2-(2-chloroacetamido)-4,5-dimethylthiophene-3-carboxylate CAS 448199-06-2
| CAS No. | 448199-06-2 |
| Molecular Formula | C10H12ClNO3S |
| Molecular Weight | 261.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 261.73 g/mol gives Methyl 2-(2-chloroacetamido)-4,5-dimethylthiophene-3-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Methyl 2-(2-chloroacetamido)-4,5-dimethylthiophene-3-carboxylate (CAS 448199-06-2), a certified reference material (molecular formula C10H12ClNO3S, MW 261.73 g/mol) for analytical method development and quality control.
The molecular framework of Methyl 2-(2-chloroacetamido)-4,5-dimethylthiophene-3-carboxylate (C10H12ClNO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Methyl 2-(2-chloroacetamido)-4,5-dimethylthiophene-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H12ClNO3S |
| Molecular Weight | 261.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- 2-(2-Chloroacetamido)-N,N,4-trimethylthiazole-5-carboxamide (CAS 545437-13-6)
- Ethyl 2-(2-chloroacetamido)-5-methylthiophene-3-carboxylate (CAS 669747-36-8)
- Ethyl 5-(2-chloroacetamido)-3-methylthiophene-2-carboxylate (CAS 285138-55-8)
- Methyl 2-(2-chloroacetamido)-3-cyclohexylpropanoate (CAS 318949-36-9)
- Ethyl 2-(2-chloroacetamido)-4-thiazoleacetate (CAS 19749-93-0)
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Recommended Standards
- Glipizide Impurity 6 (CAS 35450-53-4)
- Methyl 2-[(chloroacetyl)amino]-5-ethylthiophene-3-carboxylate (CAS 515832-73-2)
- Articaine Impurity C7 (CAS 23964-64-9)
- N-[(6-Chloroimidazo[2,1-b][1,3]thiazol-5-yl)methylene]aniline (CAS 241132-37-6)
- p-Tolyl 2-(p-tolyl)quinoline-4-carboxylate (CAS 355433-58-8)
- Methyl 4-hydroxy-6,7-diisopropoxyquinoline-3-carboxylate (CAS 1698-95-9)
- n-Hexylbicyclo[2.2.1]heptan-2-amine (CAS 1249827-61-9)
- (S)-1-(4-(difluoromethyl)-3-fluorophenyl)propan-1-amine (CAS 1213681-50-5)
- 5-bromo-1-(propan-2-yloxy)-2,3-dihydro-1H-indene (CAS 1221725-34-3)
- 6-(4-Methylpiperazin-1-yl)-2'-(m-tolyl)-1H,3'H-2,5'-bibenzo[d]imidazole (CAS 23491-54-5)
- 2,4-Difluoro-N-((1-(thiophen-2-yl)cyclopropyl)methyl)benzamide (CAS 1207059-19-5)
- Posaconazole Formylurea Analogue (CAS CATO-C4X-1208192)
- 1-Methyl-N-phenylhydrazine-1-carboxamide (CAS 19102-24-0)
- Liraglutide Impurity 28 (CAS CATO-C4X-199228)
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