2-(Benzyloxy)-5,6-difluoro-4-methyl-3-(trifluoromethyl)benzaldehyde CAS 2852767-18-9
| CAS No. | 2852767-18-9 |
| Molecular Formula | C16H11F5O2 |
| Molecular Weight | 330.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Benzyloxy)-5,6-difluoro-4-methyl-3-(trifluoromethyl)benzaldehyde.
CATO supplies 2-(Benzyloxy)-5,6-difluoro-4-methyl-3-(trifluoromethyl)benzaldehyde (CAS 2852767-18-9), a certified reference material (molecular formula C16H11F5O2, MW 330.25 g/mol) for analytical method development and quality control.
The molecular framework of 2-(Benzyloxy)-5,6-difluoro-4-methyl-3-(trifluoromethyl)benzaldehyde (C16H11F5O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(Benzyloxy)-5,6-difluoro-4-methyl-3-(trifluoromethyl)benzaldehyde under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H11F5O2 |
| Molecular Weight | 330.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F-containing |
Related Benzyloxy Standards
- 2-(Benzyloxy)-3-methoxy-β,6-dinitrostyrene (CAS 2426-62-2)
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- 4-(Benzyloxy)-3-bromoquinolin-2-ol (CAS 868145-21-5)
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Recommended Standards
- [1,1'-Biphenyl]-3,3',4,4'-tetracarboxylic acid (CAS 22803-05-0)
- 2-Iodo-1,3,5-triisopropylbenzene (CAS 2100-22-3)
- [1,1'-Biphenyl]-2,3,3',4'-tetracarboxylic acid (CAS 36978-40-2)
- 4,4′-Di-O-methylellagic acid (CAS 3374-77-4)
- N-(3-Ethynylphenyl)-benzenesulfonamide (CAS 938891-97-5)
- 1,2-Bis(di-i-propylphosphino)ethane, 98% (CAS 87532-69-2)
- 2-cyclopropyl-3-oxopropanenitrile (CAS 256376-79-1)
- Abemaciclib Impurity 183 (CAS CATO-C4X-2937183)
- N1-((1-Ethyl-1H-pyrazol-3-yl)methyl)-N2,N2-dimethylethane-1,2-diamine dihydrochloride (CAS 1856043-70-3)
- Fmoc-4-(2-fluorophenyl)-L-phenylalanine (CAS 352525-27-0)
- Venetoclax Impurity 103 (CAS CATO-C4X-2495103)
- 4-(4-Ethyl-benzyl)-piperidine (CAS 781595-51-5)
- 3-(2-Chloroacetyl)-1-(3,4-diethoxyphenyl)urea (CAS 775314-80-2)
- Semaglutide impurity 86 (CAS CATO-C4X-152686)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com