Temazepam EP Impurity E CAS 2888-64-4
| CAS No. | 2888-64-4 |
| Molecular Formula | C16H13ClN2O2 |
| Molecular Weight | 300.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Temazepam EP Impurity E.
Temazepam EP Impurity E (CAS 2888-64-4) is a high-purity analytical reference standard with the molecular formula C16H13ClN2O2 and a molecular weight of 300.74 g/mol.
The molecular framework of Temazepam EP Impurity E (C16H13ClN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Temazepam EP Impurity E meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H13ClN2O2 |
| Molecular Weight | 300.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Temazepam Standards
- Temazepam Impurity 8 (CAS 17311-35-2)
- Temazepam Related Compound F (15 mg) (7-chloro-1-methyl-5-phenyl-4,5-dihydro-1H-1,4-benzodiazepine-2,3-dione) (CAS 3294-96-0)
- Temazepam-13C,d3 (CAS 1189871-79-1)
- Temazepam-D5 (CAS 136765-51-0)
- Temazepam EP Impurity D (CAS 17191-70-7)
- Temazepam impurity G CRS (CAS 93329-92-1)
- Temazepam EP Impurity C (CAS 18818-64-9)
- Temazepam Glucuronide (CAS 3703-53-5)
Recommended Standards
- N-(5-Chloro-2-methylphenyl)-5-methylfuro[3,2-b]pyridine-2-carboxamide (CAS 941928-57-0)
- N-(3-Chloro-4-fluorophenyl)-2-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetamide (CAS 271772-66-8)
- 2-[2-(4'-Chloro-biphenyl-4-yl)-2-oxo-ethyl]acrylic Acid 4'-Chloro-|A-methylene-|A-oxo-[1,1'-biphenyl]-4-butanoic Acid 58211-82-8 (CAS 58211-82-8)
- N-(3-Chloro-2-methylphenyl)-5-methylfuro[3,2-b]pyridine-2-carboxamide (CAS 941969-55-7)
- (Z)-Pent-2-enoic acid (CAS 16666-42-5)
- B、Ba、Co、Cu、Mn、Zn、Ag、As、Be、Bi、Cd、Cr、Ni、Pb、Sb、Se、Tl、V in water quality (CAS CATO-CQCM102197)
- 2-(dimethylamino)-6-methylpyridin-3-ol (CAS 1022250-52-7)
- 1-(2,4-Difluorobenzyl)piperazin-2-one (CAS 1250306-29-6)
- N-{1-[(2,6-dimethylphenyl)carbamoyl]cyclohexyl}-N-methylpyridine-3-carboxamide (CAS 503561-73-7)
- 4-Hydroxy-2-iodobenzaldehyde (CAS 90151-01-2)
- 2,2-Difluoro-2-(Methylsulfanyl)-1-Phenylethanone (CAS 192862-16-1)
- 4-[(1E)-[(2,2,4-Trimethyl-2,3-dihydro-1-benzofuran-7-yl)imino]methyl]benzonitrile (CAS 1351483-99-2)
- 3-Chloro-2-ethoxy-9-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 88405-08-7)
- Peptide Impurity 15 (CAS 1227750-69-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com