Temazepam Glucuronide CAS 3703-53-5
| CAS No. | 3703-53-5 |
| Molecular Formula | C22H21ClN2O8 |
| Molecular Weight | 476.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 476.86 g/mol gives Temazepam Glucuronide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Temazepam Glucuronide (CAS 3703-53-5) is a high-purity analytical reference standard with the molecular formula C22H21ClN2O8 and a molecular weight of 476.86 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Temazepam Glucuronide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 476.86 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H21ClN2O8 |
| Molecular Weight | 476.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Temazepam Standards
- Temazepam EP Impurity C (CAS 18818-64-9)
- Temazepam EP Impurity D (CAS 17191-70-7)
- Temazepam impurity G CRS (CAS 93329-92-1)
- Temazepam-D5 (CAS 136765-51-0)
- Temazepam-13C,d3 (CAS 1189871-79-1)
- Temazepam Impurity 8 (CAS 17311-35-2)
- Temazepam EP Impurity E (CAS 2888-64-4)
- Temazepam Related Compound F (15 mg) (7-chloro-1-methyl-5-phenyl-4,5-dihydro-1H-1,4-benzodiazepine-2,3-dione) (CAS 3294-96-0)
Recommended Standards
- MLN-8054, >98% (HPLC) (CAS 869363-13-3)
- Meclocycline (CAS 2013-58-3)
- 1-(3-Chlorophenyl)-4-[5-(4-fluorophenyl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]piperazine (CAS 865657-93-8)
- Etoposide impurity 21 (CAS CATO-C4X-202421)
- 5-Bromo-6-(2-fluorophenyl)pyrimidin-4(3H)-one (CAS 1443289-93-7)
- Methyl 13-bromotridecanoate (CAS 80982-86-1)
- Temozolomide Metabolite-MTIC (CAS 1232679-46-7)
- 2-[4-(2-Hydroxyethyl)piperazino]-5-{(E)-[4-(methylsulfanyl)phenyl]methylidene}-1,3-thiazol-4(5H)-one (CAS 866149-76-0)
- 2-Bromo-1-chloro-4-(difluoromethoxy)benzene (CAS 1000574-90-2)
- 4-(Thiophen-2-yl)benzonitrile (CAS 15961-46-3)
- 2,3,3-Trichloroacrylic acid (CAS 2257-35-4)
- Ethyl 3,3,3-trifluoro-2-methylpropanoate (CAS 56354-75-7)
- 3-(2,3-Dihydro-1H-pyrrol-2-yl)pyridine (CAS 144648-79-3)
- Neuropeptide Y (1-24) amide (human, rat) (CAS 131448-51-6)
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