6-Chloro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridine CAS 291744-01-9
| CAS No. | 291744-01-9 |
| Molecular Formula | C13H8ClFN2 |
| Molecular Weight | 246.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Chloro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridine (CAS 291744-01-9), molecular formula C13H8ClFN2 and molecular weight 246.67 g/mol, is a CATO reference standard with documented purity and traceability.
6-Chloro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridine (C13H8ClFN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H8ClFN2 |
| Molecular Weight | 246.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 6-chloro-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide (CAS 1099139-86-2)
- 7-Chloro-2-(4-fluorophenyl)-1H-pyrrolo[2,3-c]pyridine (CAS 1447606-90-7)
- Methyl 4-chloro-3-hydroxy-5-(prop-2-yn-1-yloxy)thiophene-2-carboxylate (CAS 1707372-12-0)
- 2-(2-Chloro-6-fluorophenyl)-1h-1,3-benzodiazole (CAS 940656-93-9)
- 2-Chloro-6-(4-fluorophenyl)-4-methylnicotinonitrile (CAS 943117-82-6)
- 5-Chloro-2-(4-fluorophenyl)-1H-benzo[d]imidazole (CAS 21627-71-4)
- 6-Chloro-2-(4-fluorophenyl)imidazo[1,2-a]pyridine (CAS 2069-47-8)
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Recommended Standards
- 7-Chloro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridine (CAS 437384-07-1)
- 5,7-Dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonyl chloride (CAS 98169-74-5)
- 7-Chloro-4-methyl-2H-benzo[e][1,2,4]thiadiazin-3(4H)-one 1,1-dioxide (CAS 5790-71-6)
- 4-oxo-3,4-dihydro-2H-1-benzopyran-6-sulfonyl chloride (CAS 503470-40-4)
- 4-(Tetrahydro-2h-pyran-4-yl)butan-1-amine (CAS 1342663-58-4)
- Methyl 2-(1,4-dioxaspiro[4.5]decan-8-ylidene)acetate (CAS 172270-85-8)
- 1-Oxo-1-phenylbutan-2-yl 2-(4-chlorophenyl)-8-methylquinoline-4-carboxylate (CAS 355429-36-6)
- 2-(tert-Butyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-8-carboxylic acid (CAS 1482149-65-4)
- Ethyl 8-bromo-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylate (CAS 1254309-85-7)
- 4-Bromo-5-(methylsulfonyl)thiophene-2-carboxylic acid (CAS 172461-97-1)
- 2-Chloro-N-((tetrahydro-2H-pyran-4-yl)methyl)pyrimidin-4-amine (CAS 1224600-40-1)
- 4-Chloro-5-nitropyrimidin-2-amine (CAS 160948-35-6)
- 3-(4-Bromophenyl)oxolan-3-amine (CAS 1211596-34-7)
- Semaglutide Impurity 183 (CAS 159541-28-3)
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